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Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis.
Leimkühler, Nils B; Gleitz, Hélène F E; Ronghui, Li; Snoeren, Inge A M; Fuchs, Stijn N R; Nagai, James S; Banjanin, Bella; Lam, King H; Vogl, Thomas; Kuppe, Christoph; Stalmann, Ursula S A; Büsche, Guntram; Kreipe, Hans; Gütgemann, Ines; Krebs, Philippe; Banz, Yara; Boor, Peter; Tai, Evelyn Wing-Yin; Brümmendorf, Tim H; Koschmieder, Steffen; Crysandt, Martina; Bindels, Eric; Kramann, Rafael; Costa, Ivan G; Schneider, Rebekka K.
Afiliação
  • Leimkühler NB; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands.
  • Gleitz HFE; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands.
  • Ronghui L; Institute for Computational Genomics, Faculty of Medicine, RWTH Aachen University, Aachen 52074 Germany.
  • Snoeren IAM; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands.
  • Fuchs SNR; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands.
  • Nagai JS; Institute for Computational Genomics, Faculty of Medicine, RWTH Aachen University, Aachen 52074 Germany.
  • Banjanin B; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands.
  • Lam KH; Department of Pathology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands.
  • Vogl T; Institute of Immunology, University of Münster, Münster 49148, Germany.
  • Kuppe C; Division of Nephrology and Clinical Immunology, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany.
  • Stalmann USA; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands.
  • Büsche G; Institute of Pathology, Hannover Medical School, Hannover 30625, Germany.
  • Kreipe H; Institute of Pathology, Hannover Medical School, Hannover 30625, Germany.
  • Gütgemann I; Institute of Pathology, University of Bonn, Bonn 53127, Germany.
  • Krebs P; Institute of Pathology, University of Bern, Bern 3012, Switzerland.
  • Banz Y; Institute of Pathology, University of Bern, Bern 3012, Switzerland.
  • Boor P; Institute of Pathology, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany.
  • Tai EW; Institute of Pathology, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany.
  • Brümmendorf TH; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany.
  • Koschmieder S; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany.
  • Crysandt M; Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany.
  • Bindels E; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands.
  • Kramann R; Division of Nephrology and Clinical Immunology, Faculty of Medicine, RWTH Aachen University, Aachen 52074, Germany; Institute of Experimental Medicine and Systems Biology, RWTH Aachen University, Aachen 52074, Germany.
  • Costa IG; Institute for Computational Genomics, Faculty of Medicine, RWTH Aachen University, Aachen 52074 Germany.
  • Schneider RK; Department of Hematology, Erasmus Medical Center, Rotterdam 3015GD, the Netherlands; Department of Cell Biology, Institute for Biomedical Engineering, Faculty of Medicine, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany; Oncode Institute, Erasmus Medical Center, Rotterdam 3015GD, th
Cell Stem Cell ; 28(4): 637-652.e8, 2021 04 01.
Article em En | MEDLINE | ID: mdl-33301706
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mielofibrose Primária / Células-Tronco Mesenquimais / Transtornos Mieloproliferativos Limite: Animals / Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mielofibrose Primária / Células-Tronco Mesenquimais / Transtornos Mieloproliferativos Limite: Animals / Humans Idioma: En Revista: Cell Stem Cell Ano de publicação: 2021 Tipo de documento: Article