Total gastrectomy for severe proton pump inhibitor-induced hypomagnesemia in a MEN1/Zollinger Ellison syndrome patient.
Pancreatology
; 21(1): 236-239, 2021 Jan.
Article
em En
| MEDLINE
| ID: mdl-33309626
ABSTRACT
We report here the first case of life-threatening hypomagnesemia in a Zollinger-Ellison syndrome patient with multiple endocrine neoplasia type 1 (MEN1) syndrome. The severe symptomatic hypomagnesemia proved to be due to proton pump inhibitors (PPIs), but withdrawal of PPIs led to early severe peptic complications despite a substitution by histamine H2-receptor antagonist therapy. Simultaneous management of life-threatening hypomagnesemia, severe gastric acid hypersecretion and MEN1-associated gastrinomas was complex. A total gastrectomy was performed in order to definitely preclude the use of PPIs in this frail patient who was not eligible for curative pancreatoduodenal resection.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Síndrome de Zollinger-Ellison
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Neoplasia Endócrina Múltipla Tipo 1
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Inibidores da Bomba de Prótons
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Gastrectomia
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Deficiência de Magnésio
Limite:
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Pancreatology
Ano de publicação:
2021
Tipo de documento:
Article