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1-Methyl-1H-pyrazole-5-carboxamide Derivatives Exhibit Unexpected Acute Mammalian Toxicity.
Preston, Sarah; Garcia-Bustos, Jose; Hall, Liam G; Martin, Sheree D; Le, Thuy G; Kundu, Abhijit; Ghoshal, Atanu; Nguyen, Nghi H; Jiao, Yaqing; Ruan, Banfeng; Xue, Lian; Huang, Fei; Chang, Bill C H; McGee, Sean L; Wells, Timothy N C; Palmer, Michael J; Jabbar, Abdul; Gasser, Robin B; Baell, Jonathan B.
Afiliação
  • Preston S; School of Health and Life Sciences, Federation University, Ballarat, Victoria 3353, Australia.
  • Garcia-Bustos J; Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Hall LG; Metabolic Research Unit, Metabolic Reprogramming Laboratory, School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, Victoria 3216, Australia.
  • Martin SD; Metabolic Research Unit, Metabolic Reprogramming Laboratory, School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, Victoria 3216, Australia.
  • Le TG; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
  • Kundu A; TCG Lifesciences Private Limited, Block BN, Plot 7, Salt-lake Electronics Complex, Sector V, Kolkata 700091, West Bengal, India.
  • Ghoshal A; TCG Lifesciences Private Limited, Block BN, Plot 7, Salt-lake Electronics Complex, Sector V, Kolkata 700091, West Bengal, India.
  • Nguyen NH; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
  • Jiao Y; Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Ruan B; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
  • Xue L; Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
  • Huang F; School of Pharmaceutical Sciences, Nanjing Tech University, No. 30 South Puzhu Road, Nanjing 211816, People's Republic of China.
  • Chang BCH; Yourgene, Bioscience, Taipei 23863, Taiwan.
  • McGee SL; Metabolic Research Unit, Metabolic Reprogramming Laboratory, School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, Victoria 3216, Australia.
  • Wells TNC; Medicines for Malaria Venture, 1215 Geneva, Switzerland.
  • Palmer MJ; Medicines for Malaria Venture, 1215 Geneva, Switzerland.
  • Jabbar A; Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Gasser RB; Department of Veterinary Biosciences, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia.
  • Baell JB; School of Pharmaceutical Sciences, Nanjing Tech University, No. 30 South Puzhu Road, Nanjing 211816, People's Republic of China.
J Med Chem ; 64(1): 840-844, 2021 01 14.
Article em En | MEDLINE | ID: mdl-33352050
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Haemonchus / Antiprotozoários Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Med Chem Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Haemonchus / Antiprotozoários Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Med Chem Ano de publicação: 2021 Tipo de documento: Article