Phagocytic activity of splenic macrophages is enhanced and accompanied by cytosolic alkalinization in TRPM7 kinase-dead mice.

Beesetty, Pavani; Rockwood, Jananie; Kaitsuka, Taku; Zhelay, Tetyana; Hourani, Siham; Matsushita, Masayuki; Kozak, J Ashot

Beesetty, Pavani; Rockwood, Jananie; Kaitsuka, Taku; Zhelay, Tetyana; Hourani, Siham; Matsushita, Masayuki; Kozak, J Ashot.

Afiliação

Beesetty P; Department of Neuroscience, Cell Biology and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, OH, USA.
Rockwood J; Department of Neuroscience, Cell Biology and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, OH, USA.
Kaitsuka T; Department of Molecular Physiology, Faculty of Life Sciences, Kumamoto University, Japan.
Zhelay T; Department of Neuroscience, Cell Biology and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, OH, USA.
Hourani S; Department of Neuroscience, Cell Biology and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, OH, USA.
Matsushita M; Department of Molecular and Cellular Physiology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.
Kozak JA; Department of Neuroscience, Cell Biology and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, OH, USA.

FEBS J ; 288(11): 3585-3601, 2021 06.

Article em En | MEDLINE | ID: mdl-33354894

Assuntos

Fagocitose/genética; Trocador 1 de Sódio-Hidrogênio/genética; Baço/metabolismo; Canais de Cátion TRPM/genética; Animais; Antiácidos/farmacologia; Sinalização do Cálcio/genética; Citosol/enzimologia; Citosol/metabolismo; Células HEK293; Humanos; Macrófagos/efeitos dos fármacos; Macrófagos/metabolismo; Macrófagos/patologia; Magnésio/metabolismo; Camundongos; Fagócitos/efeitos dos fármacos; Fagócitos/metabolismo; Trocador 1 de Sódio-Hidrogênio/antagonistas & inibidores; Baço/efeitos dos fármacos

Palavras-chave

SLC9A1; alkalinization; erythrophagocytosis; ion channel; spleen

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fagocitose / Baço / Canais de Cátion TRPM / Trocador 1 de Sódio-Hidrogênio Limite: Animals / Humans Idioma: En Revista: FEBS J Ano de publicação: 2021 Tipo de documento: Article

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