OxLDL/ß2GPI/anti­ß2GPI Ab complex induces inflammatory activation via the TLR4/NF­&#954;B pathway in HUVECs.

Zhang, Guiting; Cai, Qianqian; Zhou, Hong; He, Chao; Chen, Yudan; Zhang, Peng; Wang, Ting; Xu, Liangjie; Yan, Jinchuan

OxLDL/ß2GPI/antiß2GPI Ab complex induces inflammatory activation via the TLR4/NFκB pathway in HUVECs.

Zhang, Guiting; Cai, Qianqian; Zhou, Hong; He, Chao; Chen, Yudan; Zhang, Peng; Wang, Ting; Xu, Liangjie; Yan, Jinchuan.

Afiliação

Zhang G; Department of Cardiology, Afï¬liated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.
Cai Q; Department of Laboratory Medicine, Changzheng Hospital, Second Military Medical University, Shanghai 200003, P.R. China.
Zhou H; Department of Cardiology, Afï¬liated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.
He C; Department of Clinical Laboratory and Hematology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.
Chen Y; Department of Clinical Laboratory and Hematology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.
Zhang P; Department of Clinical Laboratory and Hematology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.
Wang T; Department of Clinical Laboratory and Hematology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.
Xu L; Department of Cardiology, Afï¬liated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.
Yan J; Department of Cardiology, Afï¬liated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212013, P.R. China.

Mol Med Rep ; 23(2)2021 02.

Article em En | MEDLINE | ID: mdl-33355374

Assuntos

Anticorpos; Células Endoteliais da Veia Umbilical Humana/metabolismo; Lipoproteínas LDL; Complexos Multiproteicos; NF-kappa B/metabolismo; Transdução de Sinais/efeitos dos fármacos; Receptor 4 Toll-Like/metabolismo; beta 2-Glicoproteína I; Anticorpos/química; Anticorpos/farmacologia; Células Endoteliais da Veia Umbilical Humana/patologia; Humanos; Inflamação/induzido quimicamente; Inflamação/metabolismo; Inflamação/patologia; Lipoproteínas LDL/química; Lipoproteínas LDL/farmacologia; Monócitos/metabolismo; Monócitos/patologia; Complexos Multiproteicos/química; Complexos Multiproteicos/farmacologia; Células THP-1; beta 2-Glicoproteína I/química; beta 2-Glicoproteína I/farmacologia

Palavras-chave

oxLDL/ß2GPI/antiß2GPI Ab; HUVECs; inflammatory cytokines; adhesion molecules; TLR4; NFκB

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / NF-kappa B / Complexos Multiproteicos / Receptor 4 Toll-Like / Beta 2-Glicoproteína I / Células Endoteliais da Veia Umbilical Humana / Lipoproteínas LDL / Anticorpos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Mol Med Rep Ano de publicação: 2021 Tipo de documento: Article

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