The Jekyll and Hyde of Senescence in Cancer: TIMP1 Controls the Switch from Tumor-Controlling to Tumor-Promoting Senescence.
Cancer Cell
; 39(1): 13-15, 2021 01 11.
Article
em En
| MEDLINE
| ID: mdl-33357453
ABSTRACT
Cellular senescence is a response with two faces in cancer it restricts tumor proliferation, but it can also promote cancer progression and metastasis. In this issue of Cancer Cell, Guccini et al. uncover the role of TIMP1 in prostate cancer allowing a switch from tumor-controlling to tumor-promoting senescence.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
/
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
Limite:
Humans
/
Male
Idioma:
En
Revista:
Cancer Cell
Ano de publicação:
2021
Tipo de documento:
Article