Drug Delivery Strategies to Overcome the Blood-Brain Barrier (BBB).

Helms, Hans Christian Cederberg; Kristensen, Mie; Saaby, Lasse; Fricker, Gert; Brodin, Birger

Helms, Hans Christian Cederberg; Kristensen, Mie; Saaby, Lasse; Fricker, Gert; Brodin, Birger.

Afiliação

Helms HCC; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Kristensen M; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Saaby L; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Fricker G; Bioneer-Farma, Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Brodin B; Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls-University, Heidelberg, Germany.

Handb Exp Pharmacol ; 273: 151-183, 2022.

Article em En | MEDLINE | ID: mdl-33367937

Assuntos

Barreira Hematoencefálica; Pró-Fármacos; Transporte Biológico; Barreira Hematoencefálica/metabolismo; Encéfalo/metabolismo; Proteínas de Transporte; Fármacos do Sistema Nervoso Central/metabolismo; Sistemas de Liberação de Medicamentos; Humanos; Proteínas de Membrana Transportadoras/metabolismo; Pró-Fármacos/metabolismo

Palavras-chave

Blood-brain barrier; CNS drug delivery; CNS drug design strategies; Carrier mediated drug transport; Cell-penetrating peptides; P-glycoprotein

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Barreira Hematoencefálica Aspecto: Implementation_research Limite: Humans Idioma: En Revista: Handb Exp Pharmacol Ano de publicação: 2022 Tipo de documento: Article

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