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Relationship between vasculitis and chronic lymphocytic leukaemia: a correlation without causation.
Henderson, David Charles; Barringer, Gabrielle.
Afiliação
  • Henderson DC; Department of Family Medicine, Michigan State University College of Human Medicine, East Lansing, Michigan, USA.
  • Barringer G; Family Medicine, Mercy Health Saint Mary's, Grand Rapids, Michigan, USA.
BMJ Case Rep ; 13(12)2020 Dec 22.
Article em En | MEDLINE | ID: mdl-33370993
We report a novel case of a patient who presented with new diagnoses of both cytoplasmic antineutrophil cytoplasmic antibodies (c-ANCAs) positive vasculitis and chronic lymphocytic leukaemia (CLL). The patient was a 79-year-old man who presented with melena, haemoptysis, acute hypoxia and acute kidney injury. In the current literature, there are rare associations of c-ANCA vasculitis and malignancy, but very few, if any, relating c-ANCA vasculitis and CLL. This case is unique due to the presence of both pathologies and an uncommon presentation of the vasculitis. He presented with renal and pulmonary findings, unlike the dermal manifestations commonly seen with vasculitis. We think that this could be an easily overlooked combination of diseases and, therefore, the purpose of this case is to prevent delays in care that could affect patient outcomes and also to encourage further research into the relationship between these diseases.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Melena / Anticorpos Anticitoplasma de Neutrófilos / Vasculite Associada a Anticorpo Anticitoplasma de Neutrófilos / Injúria Renal Aguda Tipo de estudo: Diagnostic_studies Limite: Aged / Humans / Male Idioma: En Revista: BMJ Case Rep Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Melena / Anticorpos Anticitoplasma de Neutrófilos / Vasculite Associada a Anticorpo Anticitoplasma de Neutrófilos / Injúria Renal Aguda Tipo de estudo: Diagnostic_studies Limite: Aged / Humans / Male Idioma: En Revista: BMJ Case Rep Ano de publicação: 2020 Tipo de documento: Article