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Observation of an α-synuclein liquid droplet state and its maturation into Lewy body-like assemblies.
Hardenberg, Maarten C; Sinnige, Tessa; Casford, Sam; Dada, Samuel T; Poudel, Chetan; Robinson, Elizabeth A; Fuxreiter, Monika; Kaminksi, Clemens F; Kaminski Schierle, Gabriele S; Nollen, Ellen A A; Dobson, Christopher M; Vendruscolo, Michele.
Afiliação
  • Hardenberg MC; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
  • Sinnige T; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
  • Casford S; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
  • Dada ST; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
  • Poudel C; Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, UK.
  • Robinson EA; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
  • Fuxreiter M; MTA-DE Laboratory of Protein Dynamics, Department of Biochemistry and Molecular Biology, University of Debrecen, Hungary.
  • Kaminksi CF; Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, UK.
  • Kaminski Schierle GS; Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB3 0AS, UK.
  • Nollen EAA; European Research Institute for the Biology of Aging, University Medical Center Groningen, University of Groningen, Groningen 9713 AV, The Netherlands.
  • Dobson CM; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
  • Vendruscolo M; Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
J Mol Cell Biol ; 13(4): 282-294, 2021 08 04.
Article em En | MEDLINE | ID: mdl-33386842

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Corpos de Lewy / Proteínas de Caenorhabditis elegans / Alfa-Sinucleína Limite: Animals / Humans Idioma: En Revista: J Mol Cell Biol Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Corpos de Lewy / Proteínas de Caenorhabditis elegans / Alfa-Sinucleína Limite: Animals / Humans Idioma: En Revista: J Mol Cell Biol Ano de publicação: 2021 Tipo de documento: Article