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Lossless integration of multiple electronic health records for identifying pleiotropy using summary statistics.
Li, Ruowang; Duan, Rui; Zhang, Xinyuan; Lumley, Thomas; Pendergrass, Sarah; Bauer, Christopher; Hakonarson, Hakon; Carrell, David S; Smoller, Jordan W; Wei, Wei-Qi; Carroll, Robert; Velez Edwards, Digna R; Wiesner, Georgia; Sleiman, Patrick; Denny, Josh C; Mosley, Jonathan D; Ritchie, Marylyn D; Chen, Yong; Moore, Jason H.
Afiliação
  • Li R; Department of Biostatistics, Epidemiology & Informatics, University of Pennsylvania, Philadelphia, PA, USA.
  • Duan R; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  • Zhang X; Department of Biostatistics, Epidemiology & Informatics, University of Pennsylvania, Philadelphia, PA, USA.
  • Lumley T; Department of Statistics, University of Auckland, Auckland, New Zealand.
  • Pendergrass S; Biomedical and Translational Informatics Institute, Geisinger, Danville, PA, USA.
  • Bauer C; Biomedical and Translational Informatics Institute, Geisinger, Danville, PA, USA.
  • Hakonarson H; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Carrell DS; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
  • Smoller JW; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Wei WQ; Department of Biomedical Informatics, Vanderbilt University Medical Centre, Nashville, TN, USA.
  • Carroll R; Department of Biomedical Informatics, Vanderbilt University Medical Centre, Nashville, TN, USA.
  • Velez Edwards DR; Clinical and Translational Hereditary Cancer Program, Division of Genetic Medicine, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA.
  • Wiesner G; Clinical and Translational Hereditary Cancer Program, Division of Genetic Medicine, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN, USA.
  • Sleiman P; Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Denny JC; Department of Biomedical Informatics, Vanderbilt University Medical Centre, Nashville, TN, USA.
  • Mosley JD; Department of Biomedical Informatics, Vanderbilt University Medical Centre, Nashville, TN, USA.
  • Ritchie MD; Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Chen Y; Department of Biostatistics, Epidemiology & Informatics, University of Pennsylvania, Philadelphia, PA, USA. ychen123@pennmedicine.upenn.edu.
  • Moore JH; Department of Biostatistics, Epidemiology & Informatics, University of Pennsylvania, Philadelphia, PA, USA. jhmoore@upenn.edu.
Nat Commun ; 12(1): 168, 2021 01 08.
Article em En | MEDLINE | ID: mdl-33420026

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Registros Eletrônicos de Saúde / Pleiotropia Genética Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Registros Eletrônicos de Saúde / Pleiotropia Genética Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Ano de publicação: 2021 Tipo de documento: Article