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A novel ACE2 isoform is expressed in human respiratory epithelia and is upregulated in response to interferons and RNA respiratory virus infection.
Blume, Cornelia; Jackson, Claire L; Spalluto, Cosma Mirella; Legebeke, Jelmer; Nazlamova, Liliya; Conforti, Franco; Perotin, Jeanne-Marie; Frank, Martin; Butler, John; Crispin, Max; Coles, Janice; Thompson, James; Ridley, Robert A; Dean, Lareb S N; Loxham, Matthew; Reikine, Stephanie; Azim, Adnan; Tariq, Kamran; Johnston, David A; Skipp, Paul J; Djukanovic, Ratko; Baralle, Diana; McCormick, Christopher J; Davies, Donna E; Lucas, Jane S; Wheway, Gabrielle; Mennella, Vito.
Afiliação
  • Blume C; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
  • Jackson CL; Southampton NIHR Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
  • Spalluto CM; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
  • Legebeke J; Southampton NIHR Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
  • Nazlamova L; Institute for Life Sciences, University of Southampton, Southampton, UK.
  • Conforti F; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
  • Perotin JM; Faculty of Medicine, University of Southampton and Wessex Investigational Sciences Hub, Southampton, UK.
  • Frank M; School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Butler J; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
  • Crispin M; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
  • Coles J; Southampton NIHR Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
  • Thompson J; Southampton NIHR Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
  • Ridley RA; Department of Respiratory Diseases, UMRS1250, University Hospital, Reims, France.
  • Dean LSN; Biognos AB, Göteborg, Sweden.
  • Loxham M; School of Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.
  • Reikine S; Institute for Life Sciences, University of Southampton, Southampton, UK.
  • Azim A; School of Biological Sciences, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.
  • Tariq K; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
  • Johnston DA; Southampton NIHR Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
  • Skipp PJ; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
  • Djukanovic R; Southampton NIHR Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
  • Baralle D; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
  • McCormick CJ; Southampton NIHR Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
  • Davies DE; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
  • Lucas JS; Southampton NIHR Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
  • Wheway G; Faculty of Medicine, School of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
  • Mennella V; Southampton NIHR Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Nat Genet ; 53(2): 205-214, 2021 02.
Article em En | MEDLINE | ID: mdl-33432184

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Epiteliais / Enzima de Conversão de Angiotensina 2 / COVID-19 Limite: Animals / Humans Idioma: En Revista: Nat Genet Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Epiteliais / Enzima de Conversão de Angiotensina 2 / COVID-19 Limite: Animals / Humans Idioma: En Revista: Nat Genet Ano de publicação: 2021 Tipo de documento: Article