Pilot Study Using Machine Learning to Identify Immune Profiles for the Prediction of Early Virological Relapse After Stopping Nucleos(t)ide Analogues in HBeAg-Negative CHB.

Wübbolding, Maximilian; Lopez Alfonso, Juan Carlos; Lin, Chun-Yen; Binder, Sebastian; Falk, Christine; Debarry, Jennifer; Gineste, Paul; Kraft, Anke R M; Chien, Rong-Nan; Maasoumy, Benjamin; Wedemeyer, Heiner; Jeng, Wen-Juei; Meyer Hermann, Michael; Cornberg, Markus; Höner Zu Siederdissen, Christoph

Wübbolding, Maximilian; Lopez Alfonso, Juan Carlos; Lin, Chun-Yen; Binder, Sebastian; Falk, Christine; Debarry, Jennifer; Gineste, Paul; Kraft, Anke R M; Chien, Rong-Nan; Maasoumy, Benjamin; Wedemeyer, Heiner; Jeng, Wen-Juei; Meyer Hermann, Michael; Cornberg, Markus; Höner Zu Siederdissen, Christoph.

Afiliação

Wübbolding M; Department of Gastroenterology, Hepatology, and EndocrinologyHannover Medical SchoolHannoverGermany.
Lopez Alfonso JC; Centre for Individualised Infection Medicinea joint venture of Helmholtz Centre for Infection Research and Hannover Medical SchoolHannoverGermany.
Lin CY; German Center for Infection ResearchPartner-Site Hannover-BraunschweigHannoverGermany.
Binder S; Centre for Individualised Infection Medicinea joint venture of Helmholtz Centre for Infection Research and Hannover Medical SchoolHannoverGermany.
Falk C; Department of Systems Immunology and Braunschweig Integrated Centre of Systems BiologyHelmholtz Centre for Infection ResearchBraunschweigGermany.
Debarry J; Department of Gastroenterology and HepatologyChang Gung Memorial HospitalLinkou branchTaoyuanTaiwan.
Gineste P; College of MedicineChang Gung UniversityTaipeiTaiwan.
Kraft ARM; Centre for Individualised Infection Medicinea joint venture of Helmholtz Centre for Infection Research and Hannover Medical SchoolHannoverGermany.
Chien RN; Department of Systems Immunology and Braunschweig Integrated Centre of Systems BiologyHelmholtz Centre for Infection ResearchBraunschweigGermany.
Maasoumy B; Institute of Transplantation ImmunologyHannover Medical SchoolHannoverGermany.
Wedemeyer H; Centre for Individualised Infection Medicinea joint venture of Helmholtz Centre for Infection Research and Hannover Medical SchoolHannoverGermany.
Jeng WJ; TWINCOREa joint venture of Helmholtz Centre for Infection Research and Hannover Medical SchoolHannoverGermany.
Meyer Hermann M; AbivaxParisFrance.
Cornberg M; Department of Gastroenterology, Hepatology, and EndocrinologyHannover Medical SchoolHannoverGermany.
Höner Zu Siederdissen C; Centre for Individualised Infection Medicinea joint venture of Helmholtz Centre for Infection Research and Hannover Medical SchoolHannoverGermany.

Hepatol Commun ; 5(1): 97-111, 2021 01.

Article em En | MEDLINE | ID: mdl-33437904

Assuntos

Antivirais/uso terapêutico; Biomarcadores/sangue; Hepatite B Crônica/tratamento farmacológico; Hepatite B Crônica/imunologia; Hepatite B Crônica/virologia; Suspensão de Tratamento; Adulto; Idoso; DNA Viral/sangue; Feminino; Guanina/análogos & derivados; Guanina/uso terapêutico; Antígenos do Núcleo do Vírus da Hepatite B/sangue; Antígenos de Superfície da Hepatite B/sangue; Antígenos E da Hepatite B/sangue; Vírus da Hepatite B/efeitos dos fármacos; Hepatite B Crônica/sangue; Humanos; Interleucina-2/sangue; Aprendizado de Máquina; Masculino; Pessoa de Meia-Idade; Nucleosídeos/uso terapêutico; Projetos Piloto; Valor Preditivo dos Testes; Estudos Prospectivos; Recidiva; Resultado do Tratamento; Adulto Jovem

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Biomarcadores / Hepatite B Crônica / Suspensão de Tratamento Tipo de estudo: Clinical_trials / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Hepatol Commun Ano de publicação: 2021 Tipo de documento: Article

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