Assessing efficacy in important subgroups in confirmatory trials: An example using Bayesian dynamic borrowing.

Best, Nicky; Price, Robert G; Pouliquen, Isabelle J; Keene, Oliver N

Best, Nicky; Price, Robert G; Pouliquen, Isabelle J; Keene, Oliver N.

Afiliação

Best N; Department of Biostatistics, GlaxoSmithKline Research and Development, Brentford, UK.
Price RG; Department of Clinical Pharmacology Modelling & Simulation, GlaxoSmithKline Research and Development, Stevenage, Herts, UK.
Pouliquen IJ; Department of Biostatistics, GlaxoSmithKline Research and Development, Brentford, UK.
Keene ON; Department of Biostatistics, GlaxoSmithKline Research and Development, Brentford, UK.

Pharm Stat ; 20(3): 551-562, 2021 05.

Article em En | MEDLINE | ID: mdl-33475231

Assuntos

Projetos de Pesquisa; Adolescente; Teorema de Bayes; Humanos

Palavras-chave

Bayesian; borrowing; confirmatory; exacerbation; paediatric; subgroup

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Projetos de Pesquisa Tipo de estudo: Prognostic_studies Limite: Adolescent / Humans Idioma: En Revista: Pharm Stat Ano de publicação: 2021 Tipo de documento: Article

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