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Pretreatment neutrophil-to-lymphocyte ratio and mutational burden as biomarkers of tumor response to immune checkpoint inhibitors.
Valero, Cristina; Lee, Mark; Hoen, Douglas; Weiss, Kate; Kelly, Daniel W; Adusumilli, Prasad S; Paik, Paul K; Plitas, George; Ladanyi, Marc; Postow, Michael A; Ariyan, Charlotte E; Shoushtari, Alexander N; Balachandran, Vinod P; Hakimi, A Ari; Crago, Aimee M; Long Roche, Kara C; Smith, J Joshua; Ganly, Ian; Wong, Richard J; Patel, Snehal G; Shah, Jatin P; Lee, Nancy Y; Riaz, Nadeem; Wang, Jingming; Zehir, Ahmet; Berger, Michael F; Chan, Timothy A; Seshan, Venkatraman E; Morris, Luc G T.
Afiliação
  • Valero C; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Lee M; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Hoen D; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Weiss K; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Kelly DW; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Adusumilli PS; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Paik PK; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Plitas G; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Ladanyi M; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Postow MA; Information Systems, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Ariyan CE; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Shoushtari AN; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Balachandran VP; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Hakimi AA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Crago AM; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Long Roche KC; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Smith JJ; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Ganly I; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Wong RJ; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Patel SG; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Shah JP; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Lee NY; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Riaz N; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Wang J; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Zehir A; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Berger MF; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Chan TA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Seshan VE; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Morris LGT; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Nat Commun ; 12(1): 729, 2021 02 01.
Article em En | MEDLINE | ID: mdl-33526794
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Linfócitos / Inibidores de Checkpoint Imunológico / Neoplasias / Neutrófilos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Linfócitos / Inibidores de Checkpoint Imunológico / Neoplasias / Neutrófilos Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Nat Commun Ano de publicação: 2021 Tipo de documento: Article