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Paroxetine-mediated GRK2 inhibition is a disease-modifying treatment for osteoarthritis.
Carlson, Elijah L; Karuppagounder, Vengadeshprabhu; Pinamont, William J; Yoshioka, Natalie K; Ahmad, Adeel; Schott, Eric M; Le Bleu, Heather K; Zuscik, Michael J; Elbarbary, Reyad A; Kamal, Fadia.
Afiliação
  • Carlson EL; Center for Orthopedic Research and Translational Sciences, Department of Orthopedics and Rehabilitation, Penn State College of Medicine, Hershey, PA 17033, USA.
  • Karuppagounder V; Center for Orthopedic Research and Translational Sciences, Department of Orthopedics and Rehabilitation, Penn State College of Medicine, Hershey, PA 17033, USA.
  • Pinamont WJ; Center for Orthopedic Research and Translational Sciences, Department of Orthopedics and Rehabilitation, Penn State College of Medicine, Hershey, PA 17033, USA.
  • Yoshioka NK; Center for Orthopedic Research and Translational Sciences, Department of Orthopedics and Rehabilitation, Penn State College of Medicine, Hershey, PA 17033, USA.
  • Ahmad A; Center for Orthopedic Research and Translational Sciences, Department of Orthopedics and Rehabilitation, Penn State College of Medicine, Hershey, PA 17033, USA.
  • Schott EM; Solarea Bio Inc., Cambridge, MA 02142, USA.
  • Le Bleu HK; Department of Biology, University of Oregon, Eugene, OR 97403, USA.
  • Zuscik MJ; Colorado Program for Skeletal Research, Department of Orthopedics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
  • Elbarbary RA; Center for Orthopedic Research and Translational Sciences, Department of Orthopedics and Rehabilitation, Penn State College of Medicine, Hershey, PA 17033, USA.
  • Kamal F; Department of Biochemistry and Molecular Biology, Pennsylvania State College of Medicine, Hershey, PA 17033, USA.
Sci Transl Med ; 13(580)2021 02 10.
Article em En | MEDLINE | ID: mdl-33568523

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Cartilagem Articular Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Sci Transl Med Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Cartilagem Articular Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Sci Transl Med Ano de publicação: 2021 Tipo de documento: Article