A Retrospective Analysis of the Impact of Bariatric Surgery on the Management of Chronic Migraine.
Obes Surg
; 31(5): 2040-2049, 2021 May.
Article
em En
| MEDLINE
| ID: mdl-33569730
ABSTRACT
PURPOSE:
To investigate the association of the two most common bariatric surgical procedures, vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB), with sustained remission from chronic migraine. MATERIALS ANDMETHODS:
Using IBM MarketScan® research database to examine inpatient and pharmacy claims from 2010 through 2017. A cohort of bariatric patients with chronic migraine was created using inclusion and exclusion criteria. Remission was defined as no refill of first-line migraine medication for 180 days after a patients' medication was expected to run out, and recurrence as medication refill after at least 180 days of remission.RESULTS:
Of 1680 patients in our cohort, 931 (55.4%) experienced remission of migraine. Of these, 462 (49.6%) had undergone VSG, while 469 (50.4%) had undergone RYGB. Patients who underwent RYGB had an 11% (RR = 1.11, 95% CI 1.05, 1.17) increase in likelihood of remission of migraine and a 20% (RR = 0.80, 95% CI 0.63, 1.04) decrease in likelihood of recurrence of migraine compared to patients who underwent VSG. Older age group, higher number of medications at time of surgery, and female sex were associated with a decreased likelihood of remission.CONCLUSION:
Type of bariatric procedure, age, number of medications at surgery, and sex were the most important predictors of migraine remission after surgery.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Obesidade Mórbida
/
Derivação Gástrica
/
Cirurgia Bariátrica
/
Transtornos de Enxaqueca
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
Idioma:
En
Revista:
Obes Surg
Ano de publicação:
2021
Tipo de documento:
Article