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Immune-mediated thrombotic thrombocytopenic purpura in childhood treated by caplacizumab, about 3 cases.
Boudali, Julie; Hallak, Benjamin; Haeck, Marie; Sellier-Leclerc, Anne-Laure; Ulrich, Marc; Coppo, Paul; Tellier, Stéphanie; Provôt, François.
Afiliação
  • Boudali J; Department of Nephrology, CHRU Lille, Lille, France.
  • Hallak B; Department of Pediatric Nephrology and Rheumatolgy, French Reference Center of Rare Renal Diseases (SORARE), CHU Toulouse, Toulouse, France.
  • Haeck M; Department of Nephrology, CHG Valenciennes, Valenciennes, France.
  • Sellier-Leclerc AL; Department of Pediatric Nephrology, Hôpital Femme Mère Enfant, Bron, France.
  • Ulrich M; Department of Nephrology, CHG Valenciennes, Valenciennes, France.
  • Coppo P; French Reference Center for Thrombotic Microangiopathies, Hôpital Saint Antoine, AP-HP, Paris, France.
  • Tellier S; Department of Pediatric Nephrology and Rheumatolgy, French Reference Center of Rare Renal Diseases (SORARE), CHU Toulouse, Toulouse, France.
  • Provôt F; Department of Nephrology, CHRU Lille, Lille, France. francois.provot@chru-lille.fr.
J Nephrol ; 35(2): 653-656, 2022 Mar.
Article em En | MEDLINE | ID: mdl-33616856
ABSTRACT
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is a rare disease in adults and exceptional in childhood. Caplacizumab has proven its effectiveness in the treatment of iTTP in adulthood in association with standard of care. Unfortunately, this treatment is restricted to adults. We report our experience in three children who were treated successfully with caplacizumab.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Púrpura Trombocitopênica Trombótica / Anticorpos de Domínio Único Tipo de estudo: Diagnostic_studies Limite: Adult / Child / Humans Idioma: En Revista: J Nephrol Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Púrpura Trombocitopênica Trombótica / Anticorpos de Domínio Único Tipo de estudo: Diagnostic_studies Limite: Adult / Child / Humans Idioma: En Revista: J Nephrol Ano de publicação: 2022 Tipo de documento: Article