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Increased IL-6 receptor expression and signaling in ageing cartilage can be explained by loss of TGF-ß-mediated IL-6 receptor suppression.
Wiegertjes, R; Thielen, N G M; van Caam, A P M; van Laar, M; van Beuningen, H M; Koenders, M I; van Lent, P L E M; van der Kraan, P M; van de Loo, F A J; Blaney Davidson, E N.
Afiliação
  • Wiegertjes R; Department of Experimental Rheumatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Thielen NGM; Department of Experimental Rheumatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
  • van Caam APM; Department of Experimental Rheumatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
  • van Laar M; Department of Experimental Rheumatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
  • van Beuningen HM; Department of Experimental Rheumatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Koenders MI; Department of Experimental Rheumatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
  • van Lent PLEM; Department of Experimental Rheumatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
  • van der Kraan PM; Department of Experimental Rheumatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
  • van de Loo FAJ; Department of Experimental Rheumatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Blaney Davidson EN; Department of Experimental Rheumatology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address: esmeralda.blaneydavidson@radboudumc.nl.
Osteoarthritis Cartilage ; 29(5): 773-782, 2021 05.
Article em En | MEDLINE | ID: mdl-33617971

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Transdução de Sinais / Cartilagem Articular / Fator de Crescimento Transformador beta / Receptores de Interleucina-6 Limite: Animals Idioma: En Revista: Osteoarthritis Cartilage Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Transdução de Sinais / Cartilagem Articular / Fator de Crescimento Transformador beta / Receptores de Interleucina-6 Limite: Animals Idioma: En Revista: Osteoarthritis Cartilage Ano de publicação: 2021 Tipo de documento: Article