Recurrent membranous nephropathy after transplantation: donor antigen and HLA converge in defining risk.
Kidney Int
; 99(3): 545-548, 2021 03.
Article
em En
| MEDLINE
| ID: mdl-33637201
ABSTRACT
Membranous nephropathy, like many forms of glomerulonephritis, is an HLA-associated autoimmune disease that can recur in the transplanted kidney. In this issue of Kidney International, Berchtold and colleagues publish an intriguing and important paper on risk factors for recurrent post-transplant membranous nephropathy due to autoimmunity to PLA2R1. They found that the genetics of both the autoantigen and donor HLA are important determinants of the risk of recurrent disease in the graft.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Glomerulonefrite Membranosa
/
Transplante de Rim
/
Glomerulonefrite
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Kidney Int
Ano de publicação:
2021
Tipo de documento:
Article