Programmable C:G to G:C genome editing with CRISPR-Cas9-directed base excision repair proteins.

Chen, Liwei; Park, Jung Eun; Paa, Peter; Rajakumar, Priscilla D; Prekop, Hong-Ting; Chew, Yi Ting; Manivannan, Swathi N; Chew, Wei Leong

Chen, Liwei; Park, Jung Eun; Paa, Peter; Rajakumar, Priscilla D; Prekop, Hong-Ting; Chew, Yi Ting; Manivannan, Swathi N; Chew, Wei Leong.

Afiliação

Chen L; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.
Park JE; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.
Paa P; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.
Rajakumar PD; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.
Prekop HT; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.
Chew YT; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.
Manivannan SN; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore.
Chew WL; Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore, Singapore. chewwl@gis.a-star.edu.sg.

Nat Commun ; 12(1): 1384, 2021 03 02.

Article em En | MEDLINE | ID: mdl-33654077

Assuntos

Proteína 9 Associada à CRISPR/metabolismo; Sistemas CRISPR-Cas/genética; Reparo do DNA/genética; Edição de Genes; Células HEK293; Humanos; Motivos de Nucleotídeos/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Reparo do DNA / Sistemas CRISPR-Cas / Edição de Genes / Proteína 9 Associada à CRISPR Limite: Humans Idioma: En Revista: Nat Commun Ano de publicação: 2021 Tipo de documento: Article

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