Measuring the success of blinding in placebo-controlled trials: Should we be so quick to dismiss it?
J Clin Epidemiol
; 135: 176-181, 2021 07.
Article
em En
| MEDLINE
| ID: mdl-33662512
ABSTRACT
'Blinding' involves concealing knowledge of which trial participants received the interventions from participants themselves and other trial personnel throughout the trial. Blinding reduces bias arising from the beliefs and expectations of these groups. It is agreed that where possible, blinding should be attempted, for example by ensuring that experimental and control treatments look the same. However, there is a debate about if we should measure whether blinding has been successful, this manuscript will discuss this controversy, including the benefits and risks of measuring blinding within the randomised controlled trial.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Projetos de Pesquisa
/
Efeito Placebo
/
Ensaios Clínicos como Assunto
Tipo de estudo:
Clinical_trials
Limite:
Humans
Idioma:
En
Revista:
J Clin Epidemiol
Ano de publicação:
2021
Tipo de documento:
Article