Protective effects of BP-1-102 against intracranial aneurysms-induced impairments in mice.

Jiang, Zhixian; Huang, Jiaxin; You, Lingtong; Zhang, Jinning

Jiang, Zhixian; Huang, Jiaxin; You, Lingtong; Zhang, Jinning.

Afiliação

Jiang Z; Inpatient Department District N13, Quanzhou First Hospital Affiliated to Fujian Medical University, Chendong Branch of Quanzhou 1st Hospital, Quanzhou, China.
Huang J; Inpatient Department District N13, Quanzhou First Hospital Affiliated to Fujian Medical University, Chendong Branch of Quanzhou 1st Hospital, Quanzhou, China.
You L; Inpatient Department District N13, Quanzhou First Hospital Affiliated to Fujian Medical University, Chendong Branch of Quanzhou 1st Hospital, Quanzhou, China.
Zhang J; Inpatient Department District N13, Quanzhou First Hospital Affiliated to Fujian Medical University, Chendong Branch of Quanzhou 1st Hospital, Quanzhou, China.

J Drug Target ; 29(9): 974-982, 2021 11.

Article em En | MEDLINE | ID: mdl-33682559

Assuntos

Ácidos Aminossalicílicos/farmacologia; Aneurisma Roto/prevenção & controle; Aneurisma Intracraniano/tratamento farmacológico; Fator de Transcrição STAT3/antagonistas & inibidores; Sulfonamidas/farmacologia; Animais; Citocinas/metabolismo; Modelos Animais de Doenças; Inflamação/tratamento farmacológico; Inflamação/patologia; Aneurisma Intracraniano/complicações; Macrófagos/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Transdução de Sinais/efeitos dos fármacos

Palavras-chave

BP-1-102; Intracranial aneurysm (IA); inflammatory responses; macrophages infiltration; signal transducer and activator of transcription 3 (STAT3); vascular smooth muscle cells (VSMCs)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Aneurisma Intracraniano / Aneurisma Roto / Fator de Transcrição STAT3 / Ácidos Aminossalicílicos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Drug Target Ano de publicação: 2021 Tipo de documento: Article

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