Effects of Platelet-Rich Fibrin/Collagen Membrane on Sciatic Nerve Regeneration.
J Craniofac Surg
; 32(2): 794-798, 2021.
Article
em En
| MEDLINE
| ID: mdl-33705038
ABSTRACT
ABSTRACT Alternative treatment approaches to improve the regeneration ability of damaged peripheral nerves are currently under investigation. The aim of the current study was to evaluate the effects of leucocyte/platelet-rich fibrin (L-PRF) with or without a collagen membrane as a supporter on crushed sciatic nerve healing in a rat model. Recovery of motor function and electrophysiologic measurements were evaluated at 4 weeks postoperatively. The whole number of myelinated axons, peripheral nerve axon density, average nerve fiber diameter (µm), and G-ratio were analyzed and compered among the groups. Functional, electrophysiological, and histological evaluations showed no significant difference among the groups with the exception of the L-PRF with collagen membrane groups that showed relatively positive effects on the functional and histological nerve recovery. In addition, the collagen membrane with L-PRF can be effect in nerve regeneration.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fibrina Rica em Plaquetas
Limite:
Animals
Idioma:
En
Revista:
J Craniofac Surg
Ano de publicação:
2021
Tipo de documento:
Article