Nuclear Factor Erythroid 2-Related Factor 2 Activation Might Mitigate Clinical Symptoms in Friedreich's Ataxia: Clues of an "Out-Brain Origin" of the Disease From a Family Study.

Petrillo, Sara; Santoro, Massimo; La Rosa, Piergiorgio; Perna, Alessia; Gallo, Maria Giovanna; Bertini, Enrico Silvio; Silvestri, Gabriella; Piemonte, Fiorella

Petrillo, Sara; Santoro, Massimo; La Rosa, Piergiorgio; Perna, Alessia; Gallo, Maria Giovanna; Bertini, Enrico Silvio; Silvestri, Gabriella; Piemonte, Fiorella.

Afiliação

Petrillo S; Unit of Muscular and Neurodegenerative Diseases, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.
Santoro M; IRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, Italy.
La Rosa P; Division of Neuroscience, Department of Psychology, Sapienza University of Rome, Rome, Italy.
Perna A; Department of Neurosciences, Università Cattolica del Sacro Cuore, Rome, Italy.
Gallo MG; Unit of Muscular and Neurodegenerative Diseases, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.
Bertini ES; Unit of Muscular and Neurodegenerative Diseases, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy.
Silvestri G; Department of Neurosciences, Università Cattolica del Sacro Cuore, Rome, Italy.
Piemonte F; UOC of Neurology, Area of Neuroscience, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.

Front Neurosci ; 15: 638810, 2021.

Article em En | MEDLINE | ID: mdl-33708070

Palavras-chave

Friedreich ataxia; Nrf2; glutathione; neurodegenerative disease; oxidative stress

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: Front Neurosci Ano de publicação: 2021 Tipo de documento: Article

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