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Warhead Reactivity Limits the Speed of Inhibition of the Cysteine Protease Rhodesain.
Johe, Patrick; Jung, Sascha; Endres, Erik; Kersten, Christian; Zimmer, Collin; Ye, Weixiang; Sönnichsen, Carsten; Hellmich, Ute A; Sotriffer, Christoph; Schirmeister, Tanja; Neuweiler, Hannes.
Afiliação
  • Johe P; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, Staudingerweg 5, D-55128 Mainz, Germany.
  • Jung S; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, Staudingerweg 5, D-55128 Mainz, Germany.
  • Endres E; TU Dortmund University, Chemical Biology, Otto-Hahn-Str. 6, D-44227 Dortmund, Germany.
  • Kersten C; Institute for Pharmacy and Food Chemistry, Julius Maximilians University Würzburg, Am Hubland, D-97074 Würzburg, Germany.
  • Zimmer C; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, Staudingerweg 5, D-55128 Mainz, Germany.
  • Ye W; Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University Mainz, Staudingerweg 5, D-55128 Mainz, Germany.
  • Sönnichsen C; Department of Chemistry, Nanobiotechnology, Johannes Gutenberg University Mainz, Duesbergweg 10-14, D-55128 Mainz, Germany.
  • Hellmich UA; Department of Chemistry, Nanobiotechnology, Johannes Gutenberg University Mainz, Duesbergweg 10-14, D-55128 Mainz, Germany.
  • Sotriffer C; Department of Chemistry, Biochemistry, Johannes Gutenberg University Mainz, Johann-Joachim-Becherweg 30, D-55128 Mainz, Germany.
  • Schirmeister T; Centre for Biomolecular Magnetic Resonance, Goethe-University Frankfurt, Max von Laue Str. 9, D-60438 Frankfurt, Germany.
  • Neuweiler H; Institute for Pharmacy and Food Chemistry, Julius Maximilians University Würzburg, Am Hubland, D-97074 Würzburg, Germany.
ACS Chem Biol ; 16(4): 661-670, 2021 04 16.
Article em En | MEDLINE | ID: mdl-33719398
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cisteína Endopeptidases / Inibidores de Cisteína Proteinase Idioma: En Revista: ACS Chem Biol Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cisteína Endopeptidases / Inibidores de Cisteína Proteinase Idioma: En Revista: ACS Chem Biol Ano de publicação: 2021 Tipo de documento: Article