The development and validation of a high performance liquid chromatography method to determine the radiochemical purity of [<sup>177</sup>Lu]Lu-HA-DOTA-TATE in pharmaceutical preparations.

van Andel, L; Aalbersberg, E A; Geluk-Jonker, M M; Stokkel, M P M; Beijnen, J H; Hendrikx, J J M A

The development and validation of a high performance liquid chromatography method to determine the radiochemical purity of [¹⁷⁷Lu]Lu-HA-DOTA-TATE in pharmaceutical preparations.

van Andel, L; Aalbersberg, E A; Geluk-Jonker, M M; Stokkel, M P M; Beijnen, J H; Hendrikx, J J M A.

Afiliação

van Andel L; Department of Pharmacy & Pharmacology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, the Netherlands.
Aalbersberg EA; Department of Nuclear Medicine, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, the Netherlands.
Geluk-Jonker MM; Department of Pharmacy & Pharmacology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, the Netherlands; Department of Nuclear Medicine, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, the Netherlands.
Stokkel MPM; Department of Nuclear Medicine, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, the Netherlands.
Beijnen JH; Department of Pharmacy & Pharmacology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, the Netherlands; Utrecht University, Faculty of Science, Department of Pharmaceutical Sciences, Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht, the Netherlands.
Hendrikx JJMA; Department of Pharmacy & Pharmacology, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, the Netherlands; Department of Nuclear Medicine, Netherlands Cancer Institute-Antoni van Leeuwenhoek, Amsterdam, the Netherlands. Electronic address: j.hendrikx@nki.nl.

J Chromatogr B Analyt Technol Biomed Life Sci ; 1171: 122605, 2021 May 01.

Article em En | MEDLINE | ID: mdl-33740691

Assuntos

Cromatografia Líquida de Alta Pressão/métodos; Octreotida/análogos & derivados; Compostos Organometálicos; Compostos Radiofarmacêuticos; Formas de Dosagem; Modelos Lineares; Octreotida/análise; Octreotida/química; Compostos Organometálicos/análise; Compostos Organometálicos/química; Compostos Radiofarmacêuticos/análise; Compostos Radiofarmacêuticos/química; Reprodutibilidade dos Testes; Sensibilidade e Especificidade

Palavras-chave

HPLC-RA; Quality control; Radiolabelling; [(177)Lu]Lu-HA-DOTA-TATE

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Organometálicos / Octreotida / Cromatografia Líquida de Alta Pressão / Compostos Radiofarmacêuticos Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Ano de publicação: 2021 Tipo de documento: Article

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