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Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review.
Vinarov, Zahari; Abdallah, Mohammad; Agundez, José A G; Allegaert, Karel; Basit, Abdul W; Braeckmans, Marlies; Ceulemans, Jens; Corsetti, Maura; Griffin, Brendan T; Grimm, Michael; Keszthelyi, Daniel; Koziolek, Mirko; Madla, Christine M; Matthys, Christophe; McCoubrey, Laura E; Mitra, Amitava; Reppas, Christos; Stappaerts, Jef; Steenackers, Nele; Trevaskis, Natalie L; Vanuytsel, Tim; Vertzoni, Maria; Weitschies, Werner; Wilson, Clive; Augustijns, Patrick.
Afiliação
  • Vinarov Z; Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium; Department of Chemical and Pharmaceutical Engineering, Sofia University, Sofia, Bulgaria.
  • Abdallah M; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.
  • Agundez JAG; University Institute of Molecular Pathology Biomarkers, UEx. ARADyAL, Instituto de Salud Carlos III, Cáceres, Spain.
  • Allegaert K; Department of Hospital Pharmacy, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; Department of Development and Regeneration and Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
  • Basit AW; UCL School of Pharmacy, University College London, London, United Kingdom.
  • Braeckmans M; Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.
  • Ceulemans J; Pharmaceutical Sciences, Janssen Research & Development, Beerse, Belgium.
  • Corsetti M; NIHR Nottingham Biomedical Research Centre (BRC), Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom; Nottingham Digestive Diseases Centre, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
  • Griffin BT; School of Pharmacy, University College Cork, Cavanagh Pharmacy Building, Cork, Ireland.
  • Grimm M; Department of Biopharmaceutics and Pharmaceutical Technology, Center of Drug Absorption and Transport, University of Greifswald, Greifswald, Germany.
  • Keszthelyi D; Division of Gastroenterology-Hepatology, Department of Internal Medicine, NUTRIM, Maastricht University Medical Center, Maastricht, the Netherlands.
  • Koziolek M; NCE Formulation Sciences, AbbVie Deutschland GmbH & Co. KG, Ludwigshafen, Germany.
  • Madla CM; UCL School of Pharmacy, University College London, London, United Kingdom.
  • Matthys C; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium; Department of Endocrinology, University Hospitals Leuven, Leuven, Belgium.
  • McCoubrey LE; UCL School of Pharmacy, University College London, London, United Kingdom.
  • Mitra A; Clinical Pharmacology and Pharmacometrics, Janssen Research & Development, Spring House, Pennsylvania, United States.
  • Reppas C; Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Athens, Greece.
  • Stappaerts J; Pharmaceutical Sciences, Janssen Research & Development, Beerse, Belgium.
  • Steenackers N; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
  • Trevaskis NL; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.
  • Vanuytsel T; Translational Research Centre for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases, Metabolism and Ageing (ChroMeTa), KU Leuven, Leuven, Belgium.
  • Vertzoni M; Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Athens, Greece.
  • Weitschies W; Department of Biopharmaceutics and Pharmaceutical Technology, Center of Drug Absorption and Transport, University of Greifswald, Greifswald, Germany.
  • Wilson C; Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), University of Strathclyde, United Kingdom.
  • Augustijns P; Drug Delivery and Disposition, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium; Chairperson of the UNGAP network, COST CA 16205. Electronic address: patrick.augustijns@kuleuven.be.
Eur J Pharm Sci ; 162: 105812, 2021 Jul 01.
Article em En | MEDLINE | ID: mdl-33753215
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Absorção Intestinal Limite: Aged / Child / Female / Humans / Male Idioma: En Revista: Eur J Pharm Sci Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Absorção Intestinal Limite: Aged / Child / Female / Humans / Male Idioma: En Revista: Eur J Pharm Sci Ano de publicação: 2021 Tipo de documento: Article