Snoring increases the development of coronary artery disease: a systematic review with meta-analysis of observational studies.
Sleep Breath
; 25(4): 2073-2081, 2021 12.
Article
em En
| MEDLINE
| ID: mdl-33754248
ABSTRACT
PURPOSE:
Snoring is one of the cardinal presentations of obstructive sleep apnea (OSA) and is more common than OSA. Abundant evidence has suggested a robust association between OSA and coronary artery disease (CAD). However, whether or not snoring alone is related to a higher risk of CAD is unknown. This study systematically reviewed observational studies with meta-analysis to evaluate the linkage between snoring and CAD. METHODS ANDRESULTS:
We searched PubMed and Embase and retrieved 13 articles focusing on the relationship between snoring and CAD. These articles included a total of 151,366 participants and 9099 CAD patients. Quantitative analysis indicated that snoring was associated with a 28% (RR 1.28, 95% CI 1.13 to 1.45, P < 0.001) increase in the risk of developing CAD.CONCLUSIONS:
Snorers are exposed to a 28% increased risk for CAD. Although the association may be partly mediated through OSA, most snorers are not affected by apnea. Given the high prevalence of snoring and the disease burden of CAD in the general population, screening for snoring may be worthwhile for the early prevention of CAD.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ronco
/
Doença da Artéria Coronariana
/
Apneia Obstrutiva do Sono
/
Estudos Observacionais como Assunto
Tipo de estudo:
Observational_studies
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Revista:
Sleep Breath
Ano de publicação:
2021
Tipo de documento:
Article