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Response to Comment on "Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior".
Ganna, Andrea; Verweij, Karin J H; Nivard, Michel G; Maier, Robert; Wedow, Robbee; Busch, Alexander S; Abdellaoui, Abdel; Guo, Shengru; Sathirapongsasuti, J Fah; Lichtenstein, Paul; Lundström, Sebastian; Långström, Niklas; Auton, Adam; Harris, Kathleen Mullan; Beecham, Gary W; Martin, Eden R; Sanders, Alan R; Perry, John R B; Neale, Benjamin M; Zietsch, Brendan P.
Afiliação
  • Ganna A; Analytic and Translational Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Verweij KJH; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Nivard MG; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Maier R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Wedow R; Department of Psychiatry, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, Netherlands.
  • Busch AS; Department of Biological Psychology, VU University, 1081 BT Amsterdam, Netherlands.
  • Abdellaoui A; Analytic and Translational Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Guo S; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Sathirapongsasuti JF; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Lichtenstein P; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Lundström S; Department of Sociology, Harvard University, Cambridge, MA 02138, USA.
  • Långström N; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.
  • Auton A; Department of Sociology, University of Colorado, Boulder, CO 80309, USA.
  • Harris KM; Health and Society Program and Population Program, Institute of Behavioral Science, University of Colorado, Boulder, CO 80309, USA.
  • Beecham GW; Institute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA.
  • Martin ER; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.
  • Sanders AR; Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Perry JRB; International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, Copenhagen, Denmark.
  • Neale BM; Department of Psychiatry, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, Netherlands.
  • Zietsch BP; Department of Human Genetics, University of Miami, Miami, FL 33136, USA.
Science ; 371(6536)2021 03 26.
Article em En | MEDLINE | ID: mdl-33766859
ABSTRACT
Hamer et al argue that the variable "ever versus never had a same-sex partner" does not capture the complexity of human sexuality. We agree and said so in our paper. But Hamer et al neglect to mention that we also reported follow-up analyses showing substantial overlap of the genetic influences on our main variable and on more nuanced measures of sexual behavior, attraction, and identity.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Comportamento Sexual / Estudo de Associação Genômica Ampla Limite: Humans Idioma: En Revista: Science Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Comportamento Sexual / Estudo de Associação Genômica Ampla Limite: Humans Idioma: En Revista: Science Ano de publicação: 2021 Tipo de documento: Article