Tenascin-C Deficiency Is Associated With Reduced Bacterial Outgrowth During <i>Klebsiella pneumoniae</i>-Evoked Pneumosepsis in Mice.

Meijer, Mariska T; de Vos, Alex F; Scicluna, Brendon P; Roelofs, Joris J; Abou Fayçal, Chérine; Orend, Gertraud; Uhel, Fabrice; van der Poll, Tom

Tenascin-C Deficiency Is Associated With Reduced Bacterial Outgrowth During Klebsiella pneumoniae-Evoked Pneumosepsis in Mice.

Meijer, Mariska T; de Vos, Alex F; Scicluna, Brendon P; Roelofs, Joris J; Abou Fayçal, Chérine; Orend, Gertraud; Uhel, Fabrice; van der Poll, Tom.

Afiliação

Meijer MT; Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, Location Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.
de Vos AF; Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands.
Scicluna BP; Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, Location Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.
Roelofs JJ; Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands.
Abou Fayçal C; Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, Location Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.
Orend G; Amsterdam Institute for Infection and Immunity, Amsterdam University Medical Centers, Amsterdam, Netherlands.
Uhel F; Clinical Epidemiology Biostatistics and Bioinformatics, Amsterdam University Medical Centers, Location Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.
van der Poll T; Department of Pathology, Amsterdam University Medical Centers, Location Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.

Front Immunol ; 12: 600979, 2021.

Article em En | MEDLINE | ID: mdl-33776992

Assuntos

Infecções por Klebsiella/imunologia; Klebsiella pneumoniae/imunologia; Pneumonia Bacteriana/imunologia; Sepse/imunologia; Tenascina/deficiência; Animais; Infecções por Klebsiella/genética; Infecções por Klebsiella/patologia; Camundongos; Camundongos Knockout; Pneumonia Bacteriana/genética; Pneumonia Bacteriana/patologia; Sepse/genética; Sepse/patologia; Tenascina/imunologia

Palavras-chave

Klebsiella pneumoniae (K. pneumoniae); alarmins; immune system; innate immunity; mice; pneumonia; sepsis; tenascin C

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 3_ND / 4_TD Base de dados: MEDLINE Assunto principal: Infecções por Klebsiella / Sepse / Pneumonia Bacteriana / Tenascina / Klebsiella pneumoniae Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: Front Immunol Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google