New synthetic cannabinoids carrying a cyclobutyl methyl side chain: Human Phase I metabolism and data on human cannabinoid receptor 1 binding and activation of Cumyl-CBMICA and Cumyl-CBMINACA.

Haschimi, Belal; Grafinger, Katharina Elisabeth; Pulver, Benedikt; Psychou, Evangelia; Halter, Sebastian; Huppertz, Laura M; Westphal, Folker; Pütz, Michael; Auwärter, Volker

Haschimi, Belal; Grafinger, Katharina Elisabeth; Pulver, Benedikt; Psychou, Evangelia; Halter, Sebastian; Huppertz, Laura M; Westphal, Folker; Pütz, Michael; Auwärter, Volker.

Afiliação

Haschimi B; Institute of Forensic Medicine, Forensic Toxicology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Grafinger KE; Herrmann Staudinger Graduate School, University of Freiburg, Freiburg, Germany.
Pulver B; Institute of Forensic Medicine, Forensic Toxicology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Psychou E; Institute of Forensic Medicine, Forensic Toxicology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Halter S; Herrmann Staudinger Graduate School, University of Freiburg, Freiburg, Germany.
Huppertz LM; State Bureau of Criminal Investigation Schleswig-Holstein, Forensic Science Institute, Kiel, Germany.
Westphal F; Institute of Forensic Medicine, Forensic Toxicology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Pütz M; Institute of Forensic Medicine, Forensic Toxicology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Auwärter V; Herrmann Staudinger Graduate School, University of Freiburg, Freiburg, Germany.

Drug Test Anal ; 13(8): 1499-1515, 2021 Aug.

Article em En | MEDLINE | ID: mdl-33788409

Assuntos

Canabinoides/química; Canabinoides/metabolismo; Receptor CB1 de Canabinoide/metabolismo; Biotransformação; Agonistas de Receptores de Canabinoides/farmacologia; Canabinoides/urina; Guanosina 5'-O-(3-Tiotrifosfato)/metabolismo; Humanos; Hidroxilação; Drogas Ilícitas; Indazóis/química; Indazóis/metabolismo; Indóis/química; Indóis/metabolismo; Microssomos Hepáticos; Receptor CB1 de Canabinoide/agonistas

Palavras-chave

5F-Cumyl-PICA; 5F-Cumyl-PINACA; NPS; prevalence data; urine marker

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Canabinoides / Receptor CB1 de Canabinoide Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Drug Test Anal Ano de publicação: 2021 Tipo de documento: Article

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