A TOR (target of rapamycin) and nutritional phosphoproteome of fission yeast reveals novel targets in networks conserved in humans.

Halova, Lenka; Cobley, David; Franz-Wachtel, Mirita; Wang, Tingting; Morrison, Kaitlin R; Krug, Karsten; Nalpas, Nicolas; Macek, Boris; Hagan, Iain M; Humphrey, Sean J; Petersen, Janni

Halova, Lenka; Cobley, David; Franz-Wachtel, Mirita; Wang, Tingting; Morrison, Kaitlin R; Krug, Karsten; Nalpas, Nicolas; Macek, Boris; Hagan, Iain M; Humphrey, Sean J; Petersen, Janni.

Afiliação

Halova L; Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Cobley D; Cancer Research UK Manchester Institute, Alderley Park, Macclesfield SK10 4TG, UK.
Franz-Wachtel M; Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK.
Wang T; Proteome Center Tuebingen, University of Tuebingen, Auf der Morgenstelle 15, 72076 Tuebingen, Germany.
Morrison KR; Flinders Health and Medical Research Institute, Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, South Australia 5042, Australia.
Krug K; Flinders Health and Medical Research Institute, Flinders Centre for Innovation in Cancer, Flinders University, Adelaide, South Australia 5042, Australia.
Nalpas N; Proteome Center Tuebingen, University of Tuebingen, Auf der Morgenstelle 15, 72076 Tuebingen, Germany.
Macek B; Proteome Center Tuebingen, University of Tuebingen, Auf der Morgenstelle 15, 72076 Tuebingen, Germany.
Hagan IM; Proteome Center Tuebingen, University of Tuebingen, Auf der Morgenstelle 15, 72076 Tuebingen, Germany.
Humphrey SJ; Cancer Research UK Manchester Institute, Alderley Park, Macclesfield SK10 4TG, UK.
Petersen J; Charles Perkins Centre, School of Life and Environmental Sciences, The University of Sydney, Camperdown, New South Wales, Australia.

Open Biol ; 11(4): 200405, 2021 04.

Article em En | MEDLINE | ID: mdl-33823663

Assuntos

Fosfoproteínas/metabolismo; Proteoma; Proteínas de Schizosaccharomyces pombe/metabolismo; Schizosaccharomyces/metabolismo; Serina-Treonina Quinases TOR/metabolismo; Biomarcadores; Ciclo Celular/genética; Biologia Computacional; Metabolismo Energético; Ontologia Genética; Interações entre Hospedeiro e Microrganismos; Humanos; Alvo Mecanístico do Complexo 1 de Rapamicina/metabolismo; Alvo Mecanístico do Complexo 2 de Rapamicina/metabolismo; Nitrogênio/metabolismo; Fosfoproteínas/genética; Schizosaccharomyces/genética; Proteínas de Schizosaccharomyces pombe/genética; Transdução de Sinais; Estresse Fisiológico; Serina-Treonina Quinases TOR/genética

Palavras-chave

Byr1 MAPKK; TORC1; TORC2; fission yeast Schizosaccharomyces pombe; nitrogen stress; phosphoproteome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Schizosaccharomyces / Proteoma / Proteínas de Schizosaccharomyces pombe / Serina-Treonina Quinases TOR Limite: Humans Idioma: En Revista: Open Biol Ano de publicação: 2021 Tipo de documento: Article

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