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Autocrine IGF2 programmes ß-cell plasticity under conditions of increased metabolic demand.
Sandovici, Ionel; Hammerle, Constanze M; Virtue, Sam; Vivas-Garcia, Yurena; Izquierdo-Lahuerta, Adriana; Ozanne, Susan E; Vidal-Puig, Antonio; Medina-Gómez, Gema; Constância, Miguel.
Afiliação
  • Sandovici I; Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Institute of Metabolic Science, Addenbrookes Hospital, University of Cambridge, Cambridge, CB2 0QQ, UK. is299@cam.ac.uk.
  • Hammerle CM; Department of Obstetrics and Gynaecology and National Institute for Health Research, Cambridge Biomedical Research Centre, Cambridge, CB2 0SW, UK. is299@cam.ac.uk.
  • Virtue S; Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK. is299@cam.ac.uk.
  • Vivas-Garcia Y; Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Institute of Metabolic Science, Addenbrookes Hospital, University of Cambridge, Cambridge, CB2 0QQ, UK. czmh@novonordisk.com.
  • Izquierdo-Lahuerta A; Department of Obstetrics and Gynaecology and National Institute for Health Research, Cambridge Biomedical Research Centre, Cambridge, CB2 0SW, UK. czmh@novonordisk.com.
  • Ozanne SE; Novo Nordisk A/S, 2880, Bagsværd, Denmark. czmh@novonordisk.com.
  • Vidal-Puig A; Metabolic Research Laboratories and MRC Metabolic Diseases Unit, Institute of Metabolic Science, Addenbrookes Hospital, University of Cambridge, Cambridge, CB2 0QQ, UK.
  • Medina-Gómez G; Área de Bioquímica y Biología Molecular, Departamento de Ciencias Básicas de la Salud, Universidad Rey Juan Carlos, 28922, Alcorcón, Madrid, Spain.
  • Constância M; Nuffield Department of Clinical Medicine, Ludwig Institute for Cancer Research, University of Oxford, Headington, Oxford, OX3 7DQ, UK.
Sci Rep ; 11(1): 7717, 2021 04 08.
Article em En | MEDLINE | ID: mdl-33833312
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Insulin-Like II / Células Secretoras de Insulina / Plasticidade Celular Tipo de estudo: Prognostic_studies Limite: Animals / Pregnancy Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Insulin-Like II / Células Secretoras de Insulina / Plasticidade Celular Tipo de estudo: Prognostic_studies Limite: Animals / Pregnancy Idioma: En Revista: Sci Rep Ano de publicação: 2021 Tipo de documento: Article