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Ten-Year Retrospective of the Vanderbilt Institute of Chemical Biology Chemical Synthesis Core.
Kim, Kwangho; Christov, Plamen P; Romaine, Ian; Tian, Jianhua; Jana, Somnath; Lamers, Alexander P; Dutter, Brendan F; Scaggs, Toya; Jeon, Kyouk; Guttentag, Benjamin; Weaver, C David; Lindsley, Craig W; Waterson, Alex G; Sulikowski, Gary A.
Afiliação
  • Kim K; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.
  • Christov PP; Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
  • Romaine I; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.
  • Tian J; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.
  • Jana S; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.
  • Lamers AP; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.
  • Dutter BF; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.
  • Scaggs T; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.
  • Jeon K; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.
  • Guttentag B; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.
  • Weaver CD; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.
  • Lindsley CW; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.
  • Waterson AG; Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37235, United States.
  • Sulikowski GA; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.
ACS Chem Biol ; 16(5): 787-793, 2021 05 21.
Article em En | MEDLINE | ID: mdl-33877812
ABSTRACT
Chemical synthesis has been described as a central science. Its practice provides access to the chemical structures of known and/or designed function. In particular, human health is greatly impacted by synthesis that enables advancements in both basic science discoveries in chemical biology as well as translational research that can lead to new therapeutics. To support the chemical synthesis needs of investigators across campus, the Vanderbilt Institute of Chemical Biology established a chemical synthesis core as part of its foundation in 2008. Provided in this Review are examples of synthetic products, known and designed, produced in the core over the past 10 years.
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Técnicas de Química Sintética / Indicadores e Reagentes Tipo de estudo: Observational_studies Limite: Animals / Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Técnicas de Química Sintética / Indicadores e Reagentes Tipo de estudo: Observational_studies Limite: Animals / Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2021 Tipo de documento: Article