Assessment of Resistance Mechanisms and Clinical Implications in Patients with KRAS Mutated-Metastatic Breast Cancer and Resistance to CDK4/6 Inhibitors.

Raimondi, Lucrezia; Raimondi, Filippo Maria; Pietranera, Marta; Di Rocco, Arianna; Di Benedetto, Laura; Miele, Evelina; Lazzeroni, Rachele; Cimino, Giuseppe; Spinelli, Gian Paolo

Raimondi, Lucrezia; Raimondi, Filippo Maria; Pietranera, Marta; Di Rocco, Arianna; Di Benedetto, Laura; Miele, Evelina; Lazzeroni, Rachele; Cimino, Giuseppe; Spinelli, Gian Paolo.

Afiliação

Raimondi L; U.O.C. Territorial Oncology of Aprilia, Sapienza University of Rome, 04011 Aprilia, Italy.
Raimondi FM; E-Campus University, 00100 Rome, Italy.
Pietranera M; Centro Medico Diagnostico Salus, Via Cadorna 8, 00053 Civitavecchia, Italy.
Di Rocco A; Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00100 Rome, Italy.
Di Benedetto L; BIOS SpA, Via Domenico Chelini 39, 00197 Roma, Italy.
Miele E; Department of Paediatric Haematology/Oncology Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Lazzeroni R; Department of Medical and Surgical Scieces and Translational Medicine, "Sapienza" University of Rome, 00100 Rome, Italy.
Cimino G; U.O.C. Territorial Oncology of Aprilia, Sapienza University of Rome, 04011 Aprilia, Italy.
Spinelli GP; U.O.C. Territorial Oncology of Aprilia, Sapienza University of Rome, 04011 Aprilia, Italy.

Cancers (Basel) ; 13(8)2021 Apr 16.

Article em En | MEDLINE | ID: mdl-33923563

Palavras-chave

CDK4/6 inhibitors; KRAS; ddPCR; liquid biopsy; metastatic breast cancer; resistance mechanisms; targeted therapy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Aspecto: Patient_preference Idioma: En Revista: Cancers (Basel) Ano de publicação: 2021 Tipo de documento: Article

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