Factors associated with fatigue in hip and/or knee osteoarthritis: a systematic review and best evidence synthesis.
Rheumatol Adv Pract
; 5(1): rkab013, 2021.
Article
em En
| MEDLINE
| ID: mdl-33928211
ABSTRACT
OBJECTIVE:
The aim was systematically to identify and evaluate factors related to fatigue in individuals with hip and/or knee OA.METHODS:
A systematic literature search was conducted using AMED, CINAHL, MEDLINE, ProQuest and Web of Science Core Collections databases. Inclusion criteria comprised cross-sectional, case-control or longitudinal studies on patients with a diagnosis of hip and/or knee OA that included self-reported fatigue measures. Study quality was assessed using the National Heart, Lung and Blood Institute quality appraisal tool, and factors were synthesized within a bio-behavioural framework. Study designs and quality were combined to determine current evidence levels using best evidence synthesis grading. The full review protocol is available from PROSPERO (PROSPERO 2019 CRD42019138571).RESULTS:
Twenty-four studies were included, of which 19 were high, 4 moderate and 1 low quality. There was strong evidence of an association between poor self-reported physical function and high depressive symptoms with higher fatigue. Moderate evidence of an association was found between severe pain, high numbers of co-morbidities and low physical activity levels with higher fatigue. There was moderate or limited evidence of no association between most sociodemographic factors and radiographic OA severity with fatigue.CONCLUSION:
Targets for fatigue management might include improving physical function, reducing depressive symptoms, pain and co-morbidities, and increasing physical activity levels. There is a need for more rigorous longitudinal studies to understand the causal effect of fatigue determinants within the hip and knee OA populations.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Guideline
/
Observational_studies
/
Policy_brief
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Prognostic_studies
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Risk_factors_studies
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Systematic_reviews
Aspecto:
Implementation_research
Idioma:
En
Revista:
Rheumatol Adv Pract
Ano de publicação:
2021
Tipo de documento:
Article