Of 'junk food' and 'brain food': how parental diet influences offspring neurobiology and behaviour.
Trends Endocrinol Metab
; 32(8): 566-578, 2021 08.
Article
em En
| MEDLINE
| ID: mdl-33941448
ABSTRACT
Unhealthy lifestyles and mental health problems are increasingly prevalent globally. Not only are 'junk food'-induced overweight and obesity risk factors for the development of brain disorders but they are also associated intergenerationally with ill health. Here, we reflect on the current knowledge of how maternal and paternal diet influences offspring brain development and behaviour, potentially predisposing children to mental health problems. Mounting evidence indicates diet-induced maternal and paternal programming of infant metabolism and neurobehavioural function, with potential downstream effects on mental health and resilience. Beyond the central nervous system (CNS), the microbiota-gut-brain axis has emerged as an important mediator of host physiology. We discuss how intergenerational seeding of the gut microbiome via parental lineage can influence offspring gut health and neurobiology.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Exposição Paterna
/
Exposição Materna
/
Dieta
/
Eixo Encéfalo-Intestino
Tipo de estudo:
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Trends Endocrinol Metab
Ano de publicação:
2021
Tipo de documento:
Article