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Molecular imaging in MSK radiology: Where are we going?
Bauckneht, Matteo; Raffa, Stefano; Leale, Giacomo; Sambuceti, Virginia; De Cesari, Matteo; Donegani, Maria Isabella; Marini, Cecilia; Drakonaki, Eleni; Orlandi, Davide.
Afiliação
  • Bauckneht M; Nuclear Medicine, IRCCS Ospedale Policlinico San Martino, Genoa, Italy; Department of Health Sciences (DISSAL), Genoa University, Genoa, Italy.
  • Raffa S; Nuclear Medicine, IRCCS Ospedale Policlinico San Martino, Genoa, Italy; Department of Health Sciences (DISSAL), Genoa University, Genoa, Italy.
  • Leale G; Private MSK Imaging Institution, Heraklion, Crete, Greece & European University of Cyprus Medical School, Nicosia, Cyprus.
  • Sambuceti V; Postgraduate School of Radiology, Genoa University, Via Alberti 4, 16132, Genoa, Italy.
  • De Cesari M; Department of Radiology, Ospedali del Tigullio, Lavagna, Italy.
  • Donegani MI; Nuclear Medicine, IRCCS Ospedale Policlinico San Martino, Genoa, Italy; Department of Health Sciences (DISSAL), Genoa University, Genoa, Italy.
  • Marini C; Nuclear Medicine, IRCCS Ospedale Policlinico San Martino, Genoa, Italy; Institute of Molecular Bioimaging and Physiology (IBFM), National Research Council (CNR), Segrate (MI), Italy.
  • Drakonaki E; Private MSK Imaging Institution, Heraklion, Crete, Greece & European University of Cyprus Medical School, Nicosia, Cyprus.
  • Orlandi D; Department of Radiology, Ospedale Evangelico Internazionale, Corso Solferino, 1a, 16122, Genoa, Italy. Electronic address: info@dottdavideorlandi.it.
Eur J Radiol ; 140: 109737, 2021 Jul.
Article em En | MEDLINE | ID: mdl-33951567
Musculoskeletal (MSK) pathologies are one of the leading causes of disability worldwide. However, treatment options and understanding of pathogenetic processes are still partially unclear, mainly due to a limited ability in early disease detection and response to therapy assessment. In this scenario, thanks to a strong technological advancement, structural imaging is currently established as the gold-standard of diagnosis in many MSK disorders but each single diagnostic modality (plain films, high-resolution ultrasound, computed tomography and magnetic resonance) still suffer by a low specificity regarding the characterization of inflammatory processes, the quantification of inflammatory activity levels, and the degree of response to therapy. To overcome these limitations, molecular imaging techniques may play a promising role. Starting from the strengths and weaknesses of structural anatomical imaging, the present narrative review aims to highlight the promising role of molecular imaging in the assessment of non-neoplastic MSK diseases with a special focus on its role to monitor treatment response.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Radiologia / Tomografia Computadorizada por Raios X Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Eur J Radiol Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Radiologia / Tomografia Computadorizada por Raios X Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Eur J Radiol Ano de publicação: 2021 Tipo de documento: Article