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Synthesis and Evaluation of PPARδ Agonists That Promote Osteogenesis in a Human Mesenchymal Stem Cell Culture and in a Mouse Model of Human Osteoporosis.
Kress, Brian J; Kim, Dong Hyun; Mayo, Jared R; Farris, Jeffery T; Heck, Benjamin; Sarver, Jeffrey G; Andy, Divya; Trendel, Jill A; Heck, Bruce E; Erhardt, Paul W.
Afiliação
  • Kress BJ; Center for Drug Design and Development, Department of Medicinal and Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, 3000 Arlington Avenue, Toledo, Ohio 43614, United States.
  • Kim DH; Sungkyunkwan University School of Medicine, Seoul 16419, Republic of Korea.
  • Mayo JR; Northwest Ohio Stem Cure LLC, Northwest Ohio Orthopedics & Sports Medicine, Inc., Findlay, Ohio 45840, United States.
  • Farris JT; Center for Drug Design and Development, Department of Medicinal and Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, 3000 Arlington Avenue, Toledo, Ohio 43614, United States.
  • Heck B; Center for Drug Design and Development, Department of Medicinal and Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, 3000 Arlington Avenue, Toledo, Ohio 43614, United States.
  • Sarver JG; Northwest Ohio Stem Cure LLC, Northwest Ohio Orthopedics & Sports Medicine, Inc., Findlay, Ohio 45840, United States.
  • Andy D; Bluffton University, Bluffton, Ohio 45817, United States.
  • Trendel JA; Center for Drug Design and Development, Department of Medicinal and Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, 3000 Arlington Avenue, Toledo, Ohio 43614, United States.
  • Heck BE; Center for Drug Design and Development, Department of Medicinal and Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, 3000 Arlington Avenue, Toledo, Ohio 43614, United States.
  • Erhardt PW; Center for Drug Design and Development, Department of Medicinal and Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, 3000 Arlington Avenue, Toledo, Ohio 43614, United States.
J Med Chem ; 64(10): 6996-7032, 2021 05 27.
Article em En | MEDLINE | ID: mdl-33988379
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteogênese / Tiazóis / Diferenciação Celular / PPAR delta Limite: Animals / Female / Humans Idioma: En Revista: J Med Chem Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteogênese / Tiazóis / Diferenciação Celular / PPAR delta Limite: Animals / Female / Humans Idioma: En Revista: J Med Chem Ano de publicação: 2021 Tipo de documento: Article