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Authors' reply: the biologic importance of the vitamin D binding protein polymorphism in pediatric COVID-19 patients.
Bayramoglu, Elvan; Akkoç, Gülsen; Agbas, Ayse; Akgün, Özlem; Yurdakul, Kamer; Duru, Hatice Nilgün Selçuk; Elevli, Murat.
Afiliação
  • Bayramoglu E; Department of Pediatric Endocrinology, University of Health Sciences Haseki Training and Research Hospital, Istanbul, Turkey. elvanbayramoglu@gmail.com.
  • Akkoç G; Department of Pediatric Infectious Diseases, University of Health Sciences Haseki Training and Research Hospital, Istanbul, Turkey.
  • Agbas A; Department of Pediatric Nephrology, University of Health Sciences Haseki Training and Research Hospital, Istanbul, Turkey.
  • Akgün Ö; Department of Pediatrics, University of Health Sciences Haseki Training and Research Hospital, Istanbul, Turkey.
  • Yurdakul K; Department of Biochemistry, University of Health Sciences, Haseki Training and Research Hospital, Istanbul, Turkey.
  • Duru HNS; Department of Pediatrics, University of Health Sciences Haseki Training and Research Hospital, Istanbul, Turkey.
  • Elevli M; Department of Pediatrics, University of Health Sciences Haseki Training and Research Hospital, Istanbul, Turkey.
Eur J Pediatr ; 180(8): 2709-2710, 2021 Aug.
Article em En | MEDLINE | ID: mdl-33990871
What is Known? • Vitamin D has multiple roles in the immune system that can modulate the body reaction to an infection • Vitamin D binding protein (DBP) is the key transport protein which, along with albumin, binds over 99% of the circulating vitamin D metabolites What is New? • Lower 25 OH vitamin D levels were associated with higher inflammation markers, suggesting an important role of vitamin D in the clinical course of COVID-19 in children and adolescents probably by regulating the systemic inflammatory response • Further studies are warranted to investigate the possible causal association of DBP levels and polymorphism with vitamin D status (total and bioavailable vitamin D) in COVID-19 patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Biológicos / COVID-19 Limite: Adolescent / Child / Humans Idioma: En Revista: Eur J Pediatr Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Biológicos / COVID-19 Limite: Adolescent / Child / Humans Idioma: En Revista: Eur J Pediatr Ano de publicação: 2021 Tipo de documento: Article