Anemia as a Risk Factor for Organ Dysfunctions in Patients Operated on Heart Valves.
Kardiologiia
; 61(4): 39-45, 2021 May 04.
Article
em En, En
| MEDLINE
| ID: mdl-33998407
ABSTRACT
Aim To study the effects of pre- and postoperative anemia on the risk and the structure of internal organ dysfunction in patients undergoing surgery for acquired heart diseases (AHD).Material and methods This was a retrospective cohort study including 610 primarily operated patients with AHD. A comparative analysis of the incidence and the structure of internal organ dysfunction was performed, and the likelihood of intraoperative hemotransfusion was determined for patients with preoperative anemia (Hb <130âg/l) and without it. The incidence and the nature of internal organ damage were compared in patients with postoperative Hb < 90 g/l and 90-130âg/l.Results The presence of postoperative anemia detected in 45â% of patients at two days after the surgery 6-fold increased the risk of acute heart failure (odds ratio [OR], 5.75; 95â% confidence interval [CI], 1.23-26.84; Ñ=0.016), 4-fold increased the risk of multiorgan failure (MOF) (OR, 4.2; 95â% CI, 1.16-15.64; Ñ=0.03), and 5-fold increased the likelihood of hemotransfusion (OR, 4.74; 95â% CI, 3.12-7.19; Ñ<0.0001). Severe and moderate anemia (Hb <90 g/l) was observed in 11.2â% of patients, which presence 6-fold increased the risk of brain dysfunction (OR, 5.72; 95â% CI, 2.17-15.06; Ñ=0.001) and MOF (OR, 5.97; 95â% CI, 1.94-18.35; Ñ=0.004) compared to patients with Hb 90-130âg/l.Conclusion In patients with AHD, postoperative anemia increases the risk of circulatory decompensation at two days after the surgery and of MOF and also increases the likelihood of intraoperative hemotransfusion; postoperative anemia with Hb <90 g/l increases the risk of brain damage and MOF.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Anemia
/
Insuficiência de Múltiplos Órgãos
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Revista:
Kardiologiia
Ano de publicação:
2021
Tipo de documento:
Article