Cytotoxic lanostane triterpenoids from the ethanol extract of Schisandra viridis.
J Asian Nat Prod Res
; 24(4): 321-327, 2022 Apr.
Article
em En
| MEDLINE
| ID: mdl-34009066
ABSTRACT
Three new lanostane triterpenoids, designated as 6-hydroxyl schiglausin A (1), 29-hydroxyl schiglausin D (2), and 6-hydroxyl schiglausin G (3), were isolated from the ethanol extract of the stems of Schisandra viridis. Structural elucidation of all the compounds were performed by spectral methods such as 1D and 2D (1H-1H COSY, HMQC, and HMBC) NMR spectroscopy, in addition to high resolution mass spectrometry. The isolated compounds were tested in vitro for cytotoxic activities. As a result, compound 1 exhibited cytotoxic activities for all six tested human lung cancer cell lines with IC50 values less than 10 µM.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Triterpenos
/
Schisandra
Idioma:
En
Revista:
J Asian Nat Prod Res
Ano de publicação:
2022
Tipo de documento:
Article