Developing a SARS-CoV-2 Antigen Test Using Engineered Affinity Proteins.

Kim, Seunghyeon; Yee, Emma; Miller, Eric A; Hao, Yining; Tay, Dousabel M Y; Sung, Ki-Joo; Jia, Huan; Johnson, Joseph M; Saeed, Mohsan; Mace, Charles R; Yurt, Deniz Yüksel; Sikes, Hadley D

Kim, Seunghyeon; Yee, Emma; Miller, Eric A; Hao, Yining; Tay, Dousabel M Y; Sung, Ki-Joo; Jia, Huan; Johnson, Joseph M; Saeed, Mohsan; Mace, Charles R; Yurt, Deniz Yüksel; Sikes, Hadley D.

Afiliação

Kim S; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Yee E; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Miller EA; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Hao Y; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Tay DMY; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Sung KJ; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Jia H; Antimicrobial Resistance Integrated Research Group, Singapore-MIT Alliance for Research and Technology, 1 CREATE Way, Singapore 138602, Singapore.
Johnson JM; Quanterix Corporation, Billerica, MA 01821, USA.
Saeed M; Department of Biochemistry, Boston University School of Medicine, Boston, MA 02118, USA.
Mace CR; National Emerging Infectious Diseases Laboratories (NEIDL), Boston, MA 02188, USA.
Yurt DY; Department of Chemistry, Tufts University, Medford, MA 02155, USA.
Sikes HD; 3M Company, St. Paul, MN 55133, USA.

ChemRxiv ; 2021 Apr 19.

Article em En | MEDLINE | ID: mdl-34013166

Palavras-chave

affinity proteins; cellulose; cellulose binding domains; cellulose binding modules; covid-19; directed evolution; enzyme-linked immunosorbent assay; flow test strips; library screening; peptides; proteins; rapid detection test; rcSso7d; roll to roll manufacturing; thermostable protein; yeast surface display

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ChemRxiv Ano de publicação: 2021 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ChemRxiv Ano de publicação: 2021 Tipo de documento: Article