Substrate specificities and reaction kinetics of the yeast oligosaccharyltransferase isoforms.

Eyring, Jillianne; Lin, Chia-Wei; Ngwa, Elsy Mankah; Boilevin, Jérémy; Pesciullesi, Giorgio; Locher, Kaspar P; Darbre, Tamis; Reymond, Jean-Louis; Aebi, Markus

Eyring, Jillianne; Lin, Chia-Wei; Ngwa, Elsy Mankah; Boilevin, Jérémy; Pesciullesi, Giorgio; Locher, Kaspar P; Darbre, Tamis; Reymond, Jean-Louis; Aebi, Markus.

Afiliação

Eyring J; Institute of Microbiology, Department of Biology, ETH Zürich, Zürich, Switzerland.
Lin CW; Institute of Microbiology, Department of Biology, ETH Zürich, Zürich, Switzerland; Functional Genomics Center Zürich, University of Zürich/ETH Zürich, Zürich, Switzerland.
Ngwa EM; Institute of Microbiology, Department of Biology, ETH Zürich, Zürich, Switzerland.
Boilevin J; Department of Chemistry and Biochemistry, University of Berne, Bern, Switzerland.
Pesciullesi G; Department of Chemistry and Biochemistry, University of Berne, Bern, Switzerland.
Locher KP; Institute of Molecular Biology and Biophysics, Department of Biology, ETH Zürich, Zürich, Switzerland.
Darbre T; Department of Chemistry and Biochemistry, University of Berne, Bern, Switzerland.
Reymond JL; Department of Chemistry and Biochemistry, University of Berne, Bern, Switzerland.
Aebi M; Institute of Microbiology, Department of Biology, ETH Zürich, Zürich, Switzerland. Electronic address: markus.aebi@micro.biol.ethz.ch.

J Biol Chem ; 296: 100809, 2021.

Article em En | MEDLINE | ID: mdl-34023382

Assuntos

Hexosiltransferases/metabolismo; Proteínas de Membrana/metabolismo; Proteínas de Saccharomyces cerevisiae/metabolismo; Saccharomyces cerevisiae/metabolismo; Hexosiltransferases/química; Cinética; Proteínas de Membrana/química; Isoformas de Proteínas/química; Isoformas de Proteínas/metabolismo; Saccharomyces cerevisiae/química; Proteínas de Saccharomyces cerevisiae/química; Especificidade por Substrato

Palavras-chave

OST; carbohydrate structure; enzyme kinetics; glycoprotein biosynthesis; glycosylation; glycosylation inhibitor; membrane enzyme; oligosaccharyltransferase; protein complex; yeast

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Proteínas de Saccharomyces cerevisiae / Hexosiltransferases / Proteínas de Membrana Idioma: En Revista: J Biol Chem Ano de publicação: 2021 Tipo de documento: Article

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