The Association between Anemia and Parkinson's Disease: A Nested Case-Control Study Using a National Health Screening Cohort.
Brain Sci
; 11(5)2021 May 13.
Article
em En
| MEDLINE
| ID: mdl-34068124
ABSTRACT
(1) Background:
Controversy exists regarding the relationship between anemia and Parkinson's disease (PD). This study aimed to evaluate the risk of PD related to anemia in the Korean population. (2)Methods:
The Korean National Health Insurance Service-National Sample Cohort, which includes adults over 40 years of age, was assessed from 2002 to 2015. A total of 5844 PD patients were matched by age, sex, income, and region of residence with 23,376 control participants at a ratio of 14. The analyzed covariates included age, sex, blood pressure, fasting blood glucose, obesity, smoking status, and alcohol consumption. A multiple logistic regression analysis was conducted for case-control analyses. (3)Results:
The adjusted odds ratio (OR) for the risk of PD associated with anemia was 1.09 after adjusting for potential confounders (95% confidence interval (CI) 1.01-1.18, p = 0.030). Among men younger than 70 years, the adjusted OR of PD was 1.34 (95% CI 1.13-1.60, p = 0.001). (4)Conclusions:
Our findings suggest that anemia may increase the risk of PD, particularly in men younger than 70 years. Further research is required to elucidate the causal relationship between these two diseases.
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
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8_ODS3_consumo_sustancias_psicoactivas
Base de dados:
MEDLINE
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Observational_studies
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Risk_factors_studies
/
Screening_studies
Idioma:
En
Revista:
Brain Sci
Ano de publicação:
2021
Tipo de documento:
Article