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Prevalence of IgG antibodies induced by the SARS-COV-2 virus in asymptomatic adults in Nuevo Leon, Mexico.
Rodríguez-Vidales, Edgar P; Garza-Carrillo, Denise; Pérez-Trujillo, José J; Robles-Rodríguez, Olivia A; Salinas-Martínez, Ana María; Montes de Oca-Luna, Roberto; Treviño-Garza, Consuelo; De la O-Cavazos, Manuel E.
Afiliação
  • Rodríguez-Vidales EP; Health Services of the State of Nuevo Leon, Ministry of Health, Monterrey, Nuevo León, Mexico.
  • Garza-Carrillo D; Health Services of the State of Nuevo Leon, Ministry of Health, Monterrey, Nuevo León, Mexico.
  • Pérez-Trujillo JJ; Department of Histology, School of Medicine, Autonomous University of Nuevo Leon, Monterrey, Nuevo León, Mexico.
  • Robles-Rodríguez OA; Health Services of the State of Nuevo Leon, Ministry of Health, Monterrey, Nuevo León, Mexico.
  • Salinas-Martínez AM; Epidemiologic and Health Services Research Unit, Mexican Institute of Social Security, Monterrey, Nuevo León, Mexico.
  • Montes de Oca-Luna R; School of Public Health and Nutrition, Autonomous University of Nuevo Leon Monterrey, Monterrey, Nuevo León, Mexico.
  • Treviño-Garza C; Health Services of the State of Nuevo Leon, Ministry of Health, Monterrey, Nuevo León, Mexico.
  • De la O-Cavazos ME; Health Services of the State of Nuevo Leon, Ministry of Health, Monterrey, Nuevo León, Mexico.
J Med Virol ; 93(10): 5873-5879, 2021 Oct.
Article em En | MEDLINE | ID: mdl-34101203
Population-based immunoglobulin G (IgG) seroprevalence studies in asymptomatic individuals in Latin America are scarce. The objective of the study was to estimate the prevalence and geographic distribution of IgG antibodies induced by natural SARS-CoV-2 infection in asymptomatic adults, 5-8 months after the first case was reported in a northeastern state of Mexico. This was a population-based cross-sectional study carried out in Nuevo Leon during August-November 2020. Individuals ≥18 years with no previous diagnosis or symptoms suggestive of COVID-19 were consecutively screened in one of the busiest subway stations. Also, a search for eligible individuals was done from house-to-house, after selecting densely populated geographic sectors of each of the municipalities of the metropolitan area (n = 4495). The IgG antibodies to SARS-CoV-2 nucleocapsid protein were analyzed. The IgG antibody positivity rate was 27.1% (95% confidence interval [CI]: 25.8, 28.4); there were no differences by sex or age (p > 0.05). Analysis by month showed a gradual increase from 11.9% (August) to 31.9% (November); Week 39 had the highest positivity rate (42.2%, 95% CI: 34.2, 50.7). Most people did not have evidence of previous SARS-CoV-2 infection. Preventive measures and promotion of the COVID-19 vaccine should be strengthened.
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 4_TD Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Infecções Assintomáticas / SARS-CoV-2 / COVID-19 / Anticorpos Antivirais Tipo de estudo: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Mexico Idioma: En Revista: J Med Virol Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 4_TD Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Infecções Assintomáticas / SARS-CoV-2 / COVID-19 / Anticorpos Antivirais Tipo de estudo: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Mexico Idioma: En Revista: J Med Virol Ano de publicação: 2021 Tipo de documento: Article