Association of Sleep With Risk of Alzheimer's Disease Mortality: NIH-AARP Diet and Health Study.
J Appl Gerontol
; 41(4): 1057-1065, 2022 04.
Article
em En
| MEDLINE
| ID: mdl-34109847
ABSTRACT
OBJECTIVES:
Alzheimer's disease (AD) and related dementias contribute to one in three senior deaths. Lifestyle factors, including sleep, may contribute to AD risk and mortality; however, current evidence on sleep and AD mortality is mixed.METHODS:
We used data from the NIH-AARP Diet and Health Study. Sleep duration and napping were self-reported and AD death were ascertained via linkage to the National Death Index.RESULTS:
Long sleep and napping were both associated with increased AD mortality. Specifically, 9+ hr of sleep was associated with 50% increase (hazard ratio = 1.50, 95% CI = [1.17, 1.92]) in AD mortality when compared 7 to 8 hr, while napping for 1+ hr was associated with 29% increase (1.29 [1.08, 1.55]) when compared with no napping. Results appeared to be stronger in men and remained after removing AD deaths within first 5 years after baseline.DISCUSSION:
Long sleep and napping may predict higher AD mortality in the older population.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença de Alzheimer
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
/
Male
Idioma:
En
Revista:
J Appl Gerontol
Ano de publicação:
2022
Tipo de documento:
Article