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Novel Antiplasmodial Compounds Leveraged with Multistage Potency against the Parasite Plasmodium falciparum: In Vitro and In Vivo Evaluations and Pharmacokinetic Studies.
Sharma, Neha; Kashif, Mohammad; Singh, Vigyasa; Fontinha, Diana; Mukherjee, Budhaditya; Kumar, Dhruv; Singh, Shailja; Prudencio, Miguel; Singh, Agam P; Rathi, Brijesh.
Afiliação
  • Sharma N; Laboratory for Translational Chemistry and Drug Discovery, Department of Chemistry, Hansraj College University Enclave, University of Delhi, Delhi 110007, India.
  • Kashif M; Infectious Diseases Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India.
  • Singh V; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi 110067, India.
  • Fontinha D; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Avenida Professor Egas Moniz, Lisboa 1649-028, Portugal.
  • Mukherjee B; School of Medical Science and Technology, IIT Kharagpur, Kharagpur 721302, India.
  • Kumar D; Amity Institute of Molecular Medicine & Stem Cell Research, Amity University, Noida 201301, Uttar Pradesh, India.
  • Singh S; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi 110067, India.
  • Prudencio M; Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Avenida Professor Egas Moniz, Lisboa 1649-028, Portugal.
  • Singh AP; Infectious Diseases Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India.
  • Rathi B; Laboratory for Translational Chemistry and Drug Discovery, Department of Chemistry, Hansraj College University Enclave, University of Delhi, Delhi 110007, India.
J Med Chem ; 64(12): 8666-8683, 2021 06 24.
Article em En | MEDLINE | ID: mdl-34124905
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 2_ODS3 / 3_ND Base de dados: MEDLINE Assunto principal: Piperazinas / Plasmodium falciparum / Etanolaminas / Malária / Antimaláricos Limite: Animals Idioma: En Revista: J Med Chem Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 2_ODS3 / 3_ND Base de dados: MEDLINE Assunto principal: Piperazinas / Plasmodium falciparum / Etanolaminas / Malária / Antimaláricos Limite: Animals Idioma: En Revista: J Med Chem Ano de publicação: 2021 Tipo de documento: Article