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HIF-1α and HIF-2α redundantly promote retinal neovascularization in patients with ischemic retinal disease.
Zhang, Jing; Qin, Yaowu; Martinez, Mireya; Flores-Bellver, Miguel; Rodrigues, Murilo; Dinabandhu, Aumreetam; Cao, Xuan; Deshpande, Monika; Qin, Yu; Aparicio-Domingo, Silvia; Rui, Yuan; Tzeng, Stephany Y; Salman, Shaima; Yuan, Jin; Scott, Adrienne W; Green, Jordan J; Canto-Soler, M Valeria; Semenza, Gregg L; Montaner, Silvia; Sodhi, Akrit.
Afiliação
  • Zhang J; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Qin Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, China.
  • Martinez M; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Flores-Bellver M; Eye, Ear, Nose and Throat Hospital, Fudan University, Shanghai, China.
  • Rodrigues M; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Dinabandhu A; CellSight, Ocular Stem Cell and Regeneration Research Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado School of Medicine, Aurora, Colorado, USA.
  • Cao X; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Deshpande M; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Qin Y; Department of Oncology and Diagnostic Sciences, School of Dentistry, Greenebaum Cancer Center, University of Maryland, Baltimore, Maryland, USA.
  • Aparicio-Domingo S; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Rui Y; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Tzeng SY; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Salman S; Department of Ophthalmology, Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, Key Lens Research Laboratory of Liaoning Province, Shenyang, Liaoning, China.
  • Yuan J; CellSight, Ocular Stem Cell and Regeneration Research Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado School of Medicine, Aurora, Colorado, USA.
  • Scott AW; Department of Biomedical Engineering, Institute for NanoBioTechnology, and Translational Tissue Engineering Center, and.
  • Green JJ; Department of Biomedical Engineering, Institute for NanoBioTechnology, and Translational Tissue Engineering Center, and.
  • Canto-Soler MV; Departments of Pediatrics, Medicine, Oncology, Radiation Oncology, Biological Chemistry, and Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Semenza GL; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, China.
  • Montaner S; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Sodhi A; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
J Clin Invest ; 131(12)2021 06 15.
Article em En | MEDLINE | ID: mdl-34128478
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vasos Retinianos / Neovascularização Retiniana / Regulação da Expressão Gênica / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Subunidade alfa do Fator 1 Induzível por Hipóxia / Anemia Falciforme Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vasos Retinianos / Neovascularização Retiniana / Regulação da Expressão Gênica / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Subunidade alfa do Fator 1 Induzível por Hipóxia / Anemia Falciforme Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2021 Tipo de documento: Article