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A preclinical report of a cobimetinib-inspired novel anticancer small-molecule scaffold of isoflavones, NSC777213, for targeting PI3K/AKT/mTOR/MEK in multiple cancers.
Lawal, Bashir; Lo, Wen-Cheng; Mokgautsi, Ntlotlang; Sumitra, Maryam Rachmawati; Khedkar, Harshita; Wu, Alexander Th; Huang, Hsu-Shan.
Afiliação
  • Lawal B; PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica Taipei 11031, Taiwan.
  • Lo WC; Graduate Institute for Cancer Biology & Drug Discovery, College of Medical Science and Technology, Taipei Medical University Taipei 11031, Taiwan.
  • Mokgautsi N; Department of Surgery, Division of Neurosurgery, School of Medicine, College of Medicine, Taipei Medical University Taipei 11031, Taiwan.
  • Sumitra MR; Department of Neurosurgery, Taipei Medical University Hospital Taipei 11031, Taiwan.
  • Khedkar H; Taipei Neuroscience Institute, Taipei Medical University Taipei 11031, Taiwan.
  • Wu AT; PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica Taipei 11031, Taiwan.
  • Huang HS; Graduate Institute for Cancer Biology & Drug Discovery, College of Medical Science and Technology, Taipei Medical University Taipei 11031, Taiwan.
Am J Cancer Res ; 11(6): 2590-2617, 2021.
Article em En | MEDLINE | ID: mdl-34249417
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Am J Cancer Res Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Am J Cancer Res Ano de publicação: 2021 Tipo de documento: Article